SCHEMBL15422384

SCHEMBL15422384

Brc1ccc(-c2nnc(-c3ccc(Br)s3)nn2)s1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
HSD17B10 Q99714 2/20 0.45
ALOX12 P18054 2/20 0.45
ALOX15 P16050 1/20 0.45
KDM4E B2RXH2 4/20 0.42
RAB9A P51151 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
RXFP1 Q9HBX9 3/20 0.42
NPC1 O15118 2/20 0.42
ALDH1A1 P00352 2/20 0.42
PPARG P37231 2/20 0.42
NCOA2 Q15596 2/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
NCOA1 Q15788 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
NCOA3 Q9Y6Q9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197157 0.80 SNCA (0.50) MAPTMEN1KMT2AHSD17B10ALOX12
SCHEMBL7865703 0.78 HDAC1 (0.52) MAPTMEN1KMT2AHSD17B10ALOX12
SCHEMBL5453288 0.77 SNCA (0.48) MAPTMEN1KMT2AHSD17B10ALOX12
SCHEMBL5889194 0.77 SNCA (0.48) MAPTMEN1KMT2AHSD17B10ALOX12
SCHEMBL5889177 0.77 SNCA (0.48) MAPTMEN1KMT2AHSD17B10ALOX12
SCHEMBL2215941 0.77 ATM (0.48) MEN1KMT2AKDM4EALDH1A1L3MBTL1
SCHEMBL4011780 0.75 MAPT (0.52) MAPTMEN1KMT2AHSD17B10ALOX12
SCHEMBL2275020 0.74 MAPT (0.35) MAPTMEN1KMT2AHSD17B10ALOX12
SCHEMBL2898484 0.74 EPHX2 (0.36) MAPTMEN1KMT2AHSD17B10ALOX12
SCHEMBL2778388 0.72 SNCA (0.61) MAPTMEN1KMT2AHSD17B10ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112409375-A Organic small-molecule photovoltaic material based on tetrazine derivative 东华理工大学 2021-02-26 CN disclosed
US-20170174826-A1 DONOR-ACCEPTOR POLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-06-22 US disclosed
US-20170174826-A1 DONOR-ACCEPTOR POLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-06-22 US disclosed
US-20170174826-A1 DONOR-ACCEPTOR POLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-06-22 US disclosed
WO-2016010485-A1 DONOR-ACCEPTOR POLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2016-01-21 WO disclosed
WO-2016010485-A1 DONOR-ACCEPTOR POLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2016-01-21 WO disclosed
US-8912535-B2 Naphthalene-diimide-heterocycle-naphthalene diimide oligomers as organic semiconductors and transistors therefrom GEORGIA TECH RESEARCH CORPORATION (US) 2014-12-16 US disclosed
US-8912535-B2 Naphthalene-diimide-heterocycle-naphthalene diimide oligomers as organic semiconductors and transistors therefrom GEORGIA TECH RESEARCH CORPORATION (US) 2014-12-16 US disclosed
US-8912535-B2 Naphthalene-diimide-heterocycle-naphthalene diimide oligomers as organic semiconductors and transistors therefrom GEORGIA TECH RESEARCH CORPORATION (US) 2014-12-16 US disclosed
US-20140021448-A1 NAPHTHALENE-DIIMIDE-HETEROCYCLE-NAPHTHALENE DIIMIDE OLIGOMERS AS ORGANIC SEMICONDUCTORS AND TRANSISTORS THEREFROM GEORGIA TECH RESEARCH CORPORATION (US) 2014-01-23 US disclosed
US-20140021448-A1 NAPHTHALENE-DIIMIDE-HETEROCYCLE-NAPHTHALENE DIIMIDE OLIGOMERS AS ORGANIC SEMICONDUCTORS AND TRANSISTORS THEREFROM GEORGIA TECH RESEARCH CORPORATION (US) 2014-01-23 US disclosed
US-20140021448-A1 NAPHTHALENE-DIIMIDE-HETEROCYCLE-NAPHTHALENE DIIMIDE OLIGOMERS AS ORGANIC SEMICONDUCTORS AND TRANSISTORS THEREFROM GEORGIA TECH RESEARCH CORPORATION (US) 2014-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170174826-A1 DONOR-ACCEPTOR POLYMERS TST, ETFA, SQOR MAPT 2892/4885MEN1 4331/4885KMT2A 2564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.