Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1A | O00555 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029295 | 0.89 | MMP2 (0.36) | CACNA1ACACNA2D1CACNB1NPC1RAB9A | |
| SCHEMBL132431 | 0.82 | CACNA1A (0.40) | CACNA1ACACNA2D1CACNB1CYP1A2CYP3A4 | |
| SCHEMBL27170339 | 0.82 | CACNA1A (0.43) | CACNA1ACACNA2D1CACNB1CYP1A2CYP3A4 | |
| SCHEMBL15422728 | 0.80 | PTGES (0.36) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL224452 | 0.79 | MMP2 (0.36) | CACNA1ACACNA2D1CACNB1PPARA | |
| SCHEMBL3830756 | 0.78 | NPC1 (0.45) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL4941317 | 0.77 | NPC1 (0.41) | CACNA1ACACNA2D1CACNB1CYP1A2CYP3A4 | |
| SCHEMBL28548681 | 0.76 | NPC1 (0.34) | CACNA1ACACNA2D1CACNB1CYP1A2CYP3A4 | |
| SCHEMBL25355838 | 0.75 | L3MBTL1 (0.34) | CACNA1ACACNA2D1CACNB1NPC1RAB9A | |
| SCHEMBL208253 | 0.75 | PRKCZ (0.32) | CACNA1ACACNA2D1CACNB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657228-B2 | Performance boosting UV-absorbing compounds | ISP INVESTMENTS LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-20140023601-A1 | PERFORMANCE BOOSTING UV-ABSORBING COMPOUNDS | ISP INVESTMENT INC. (US) | 2014-01-23 | — | — | US | disclosed |