SCHEMBL15424233

SCHEMBL15424233

Nc1cccc2cc(S(=O)(=O)O)c(/N=N/c3ccccc3)c(O)c12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHLPP2 Q6ZVD8 1/20 0.58
ENPP2 Q13822 8/20 0.57
CYP1A2 P05177 3/20 0.56
SUMO2 P61956 3/20 0.49
SUMO1 P63165 3/20 0.49
SENP7 Q9BQF6 3/20 0.49
SENP2 Q9HC62 3/20 0.49
CYP2C9 P11712 1/20 0.49
MAPK1 P28482 1/20 0.49
DNASE1L3 Q13609 1/20 0.49
GLO1 Q04760 1/20 0.48
PRMT3 O60678 1/20 0.47
EP300 Q09472 1/20 0.47
PRMT6 Q96LA8 1/20 0.47
PRMT1 Q99873 1/20 0.47
MEN1 O00255 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
SENP1 Q9P0U3 2/20 0.46
SENP3 Q9H4L4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12260113 0.91 PHLPP2 (0.65) PHLPP2ENPP2CYP1A2SUMO2SUMO1
SCHEMBL13619049 0.90 PHLPP2 (0.56) PHLPP2ENPP2CYP1A2SUMO2SUMO1
SCHEMBL13631320 0.90 PHLPP2 (0.56) PHLPP2ENPP2CYP1A2SUMO2SUMO1
SCHEMBL15268155 0.90 PHLPP2 (0.70) PHLPP2ENPP2CYP1A2SUMO2SUMO1
SCHEMBL13619053 0.87 ENPP2 (0.58) PHLPP2ENPP2CYP1A2SUMO2SUMO1
SCHEMBL113323 0.85 PHLPP2 (0.70) PHLPP2ENPP2CYP1A2SUMO2SUMO1
SCHEMBL29377534 0.85 PHLPP2 (0.70) PHLPP2ENPP2CYP1A2SUMO2SUMO1
SCHEMBL186095 0.85 PHLPP2 (0.70) PHLPP2ENPP2CYP1A2SUMO2SUMO1
SCHEMBL344209 0.85 PHLPP2 (0.70) PHLPP2ENPP2CYP1A2SUMO2SUMO1
SCHEMBL5590892 0.85 ENPP2 (0.58) PHLPP2ENPP2CYP1A2SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 US disclosed
US-8932370-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2015-01-13 US disclosed
US-8758451-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2014-06-24 US disclosed
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 PHLPP2 3191/4885ENPP2 2897/4885CYP1A2 1159/4885
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 PHLPP2 3191/4885ENPP2 2897/4885CYP1A2 1159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.