SCHEMBL13619053

SCHEMBL13619053

Nc1cccc2cc(S(=O)(=O)O)c(N=Nc3ccc(C(=O)Nc4ccccc4)cc3)c(O)c12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 6/20 0.58
PHLPP2 Q6ZVD8 1/20 0.49
PRMT3 O60678 1/20 0.49
EP300 Q09472 1/20 0.49
PRMT6 Q96LA8 1/20 0.49
PRMT1 Q99873 1/20 0.49
NQO2 P16083 1/20 0.49
CYP1A2 P05177 2/20 0.47
MEN1 O00255 2/20 0.44
HTT P42858 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
NCOR2 Q9Y618 1/20 0.44
GLO1 Q04760 1/20 0.43
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12906889 0.88 ENPP2 (0.58) ENPP2PHLPP2PRMT3EP300PRMT6
SCHEMBL15424233 0.87 PHLPP2 (0.58) ENPP2PHLPP2PRMT3EP300PRMT6
SCHEMBL13432578 0.85 ENPP2 (0.58) ENPP2PHLPP2PRMT3EP300PRMT6
SCHEMBL12260113 0.82 PHLPP2 (0.65) ENPP2PHLPP2PRMT1CYP1A2MEN1
SCHEMBL13631320 0.81 PHLPP2 (0.56) ENPP2PHLPP2PRMT3EP300PRMT6
SCHEMBL15268155 0.81 PHLPP2 (0.70) ENPP2PHLPP2PRMT1CYP1A2MEN1
SCHEMBL13619049 0.81 PHLPP2 (0.56) ENPP2PHLPP2CYP1A2MEN1HTT
SCHEMBL15268146 0.79 PHLPP2 (0.50) ENPP2PHLPP2PRMT3EP300PRMT6
SCHEMBL29637841 0.79 ENPP2 (0.57) ENPP2PHLPP2PRMT3EP300PRMT6
SCHEMBL17540334 0.77 PRMT3 (0.68) ENPP2PHLPP2PRMT3EP300PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619074-B2 Reactive dyestuff with N,N-dialkylamino bridge group EVERLIGHT USA, INC. (US) 2009-11-17 US disclosed
US-20090176972-A1 Novel reactive dyestuff with N,N-dialkylamino bridge group EVERLIGHT USA, INC. (US) 2009-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090176972-A1 Novel reactive dyestuff with N,N-dialkylamino bridge group SRM, PADI1, NOS1 ENPP2 4431/4885PHLPP2 4316/4885PRMT3 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.