Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159294 | 0.85 | HTR2B (0.37) | HTR2AHTR2CHTR1ADRD2DRD4 | |
| SCHEMBL19314096 | 0.81 | GABRA1 (0.38) | GABRA1GABRB2HTR2AHTR2CHTR1A | |
| SCHEMBL9502970 | 0.76 | GABRA1 (0.42) | GABRA1GABRB2HTR1AKDM4EALDH1A1 | |
| SCHEMBL4436510 | 0.72 | PARP1 (0.36) | ALDH1A1CYP1A2TSHR | |
| SCHEMBL12961126 | 0.72 | GABRA1 (0.36) | GABRA1GABRB2HTR2AHTR2CTAAR1 | |
| SCHEMBL5300479 | 0.72 | GABRA1 (0.36) | GABRA1GABRB2HTR2AHTR2CHTR1A | |
| SCHEMBL7473196 | 0.71 | HTR2C (0.43) | HTR2AHTR2CHTR1AHTR2BKDM4E | |
| SCHEMBL3533548 | 0.70 | LMNA (0.49) | CYP1A2 | |
| SCHEMBL192953 | 0.68 | CD44 (0.38) | HTR2AKDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL17288962 | 0.68 | PARP10 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002517459-A | — | — | 2002-06-18 | — | — | JP | claimed |
| EP-1019360-A1 | $g(b)2-ADRENERGIC RECEPTOR AGONISTS | Advanced Medicine, Inc. (US) | 2000-07-19 | — | — | EP | claimed |
| EP-1019360-A4 | $g(b)2-ADRENERGIC RECEPTOR AGONISTS | ADVANCED MEDICINE INC (US) | 2000-07-19 | — | — | EP | claimed |
| WO-1999064034-A1 | β2-ADRENERGIC RECEPTOR AGONISTS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | claimed |
| CN-118354770-A | Flavonoid derivatives having GABAA receptor activity and methods of use | 罗特格斯新泽西州立大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-118317943-A | Synthesis method of chiral 3, 5-disubstituted morpholine compound and useful intermediate thereof | 百济神州有限公司 | 2024-07-09 | — | — | CN | disclosed |
| WO-2024140935-A1 | B7H3 ANTIBODY DRUG CONJUGATES | BEIGENE, LTD. (KY) | 2024-07-04 | — | — | WO | disclosed |
| WO-2024140678-A1 | A KETAL PROTECTED INTERMEDIATE FOR SONROTOCLAX AND PREPARATION METHOD THEREOF | BEIGENE (SUZHOU) CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |
| WO-2024140690-A1 | INTERMEDIATES OF SONROTOCLAX AND THE METHOD OF PREPARING THE SAME | BEIGENE (SUZHOU) CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |
| WO-2024145273-A2 | N-MYRISTOYLTRANSFERASE INHIBITORS AND METHODS OF USE | SEATTLE CHILDREN'S HOSPITAL (D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE) (US) | 2024-07-04 | — | — | WO | disclosed |
| EP-4392168-A1 | IONIC LIQUID-BASED COMPOSITE MEMBRANES USING FUNCTIONAL CROSS-LINKERS | The Regents of the University of Colorado, a body corporate (US) | 2024-07-03 | — | — | EP | disclosed |
| EP-4392430-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | Yale University (US) | 2024-07-03 | — | — | EP | disclosed |
| US-20060276410-A1 | COMPOUNDS AND METHODS FOR SELECTIVE INHIBITION OF DIPEPTIDYL PEPTIDASE-IV | Forest Laboratories Holding Limited (BM) | 2006-12-07 | — | — | US | disclosed |
| US-20060258621-A1 | PYRROLIDINE COMPOUNDS AND METHODS FOR SELECTIVE INHIBITION OF DIPEPTIDYL PEPTIDASE-IV | SINO-MED INTERNATIONAL ALLIANCE, INC. | 2006-11-16 | — | — | US | disclosed |
| US-20060252851-A1 | Urethanes, ureas or esters of thiocarbamic acid, for use with fillers in the preparation of polymer composites and nanocomposites; compatibility between the filler and hydrophobic polymers such as polyolefins | THE UNIVERSITY OF CHICAGO | 2006-11-09 | — | — | US | disclosed |
| US-20060205728-A1 | Novel scaffolds for beta-helix mimicry | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-09-14 | — | — | US | disclosed |
| WO-2006091737-A1 | MODULATORS OF GSK-3 ACTIVITY | KEMIA, INC. (US) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006091862-A2 | CYTOKINE INHIBITORS AND THEIR USE IN THERAPY | KEMIA, INC. (US) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006017292-A1 | CONSTRAINED CYANO COMPOUNDS | PHENOMIX CORPORATION (US) | 2006-02-16 | — | — | WO | disclosed |
| US-20060009518-A1 | Constrained cyano compounds | Forest Laboratories Holding Limited (BM) | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276410-A1 | COMPOUNDS AND METHODS FOR SELECTIVE INHIBITION OF DIPEPTIDYL PEPTIDASE-IV | DPP4, DPP3, DPP7 | GABRA1 3417/4885GABRB2 2289/4885HTR2A 3733/4885 |
| US-20060009518-A1 | Constrained cyano compounds | DNPEP, PREP, PEPD | GABRA1 2798/4885GABRB2 1407/4885HTR2A 3156/4885 |
| US-20060205728-A1 | Novel scaffolds for beta-helix mimicry | HRH1, HEATR1, HSPH1 | GABRA1 506/4885GABRB2 169/4885HTR2A 269/4885 |
| US-20060258621-A1 | PYRROLIDINE COMPOUNDS AND METHODS FOR SELECTIVE INHIBITION OF DIPEPTIDYL PEPTIDASE-IV | DPP4, DPP7, DPP3 | GABRA1 1231/4885GABRB2 956/4885HTR2A 3942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.