Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1956497 | 0.89 | RXFP1 (0.34) | L3MBTL1RXFP1 | |
| SCHEMBL37429 | 0.87 | RXFP1 (0.35) | L3MBTL1RXFP1 | |
| SCHEMBL12688317 | 0.85 | ALDH1A1 (0.37) | L3MBTL1RXFP1KDM4EALDH1A1HPGD | |
| SCHEMBL12688302 | 0.81 | L3MBTL1 (0.36) | L3MBTL1RXFP1 | |
| SCHEMBL15032112 | 0.80 | L3MBTL1 (0.35) | L3MBTL1RXFP1KDM4EALDH1A1 | |
| SCHEMBL15032115 | 0.80 | RXFP1 (0.32) | RXFP1KDM4EALDH1A1 | |
| SCHEMBL15032128 | 0.79 | L3MBTL1 (0.35) | L3MBTL1RXFP1 | |
| SCHEMBL14998149 | 0.79 | RXFP1 (0.32) | L3MBTL1RXFP1 | |
| SCHEMBL1955250 | 0.79 | — | — | |
| SCHEMBL15032117 | 0.78 | RXFP1 (0.34) | L3MBTL1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507240-B1 | SPIRO FUSED 1-AMINO-PIPERIDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-15 | — | — | EP | disclosed |