Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12688312 | 0.93 | RAB9A (0.35) | MAPTPOLBRAB9AHPGDRXFP1 | |
| SCHEMBL15424657 | 0.85 | L3MBTL1 (0.35) | ALDH1A1KDM4EHPGDRXFP1L3MBTL1 | |
| SCHEMBL1956497 | 0.84 | RXFP1 (0.34) | RXFP1L3MBTL1 | |
| SCHEMBL12573634 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTMAPK1POLBTDP1 | |
| SCHEMBL37429 | 0.82 | RXFP1 (0.35) | RXFP1L3MBTL1 | |
| SCHEMBL12456817 | 0.80 | ALDH1A1 (0.35) | ALDH1A1MAPTMAPK1POLBTDP1 | |
| SCHEMBL12573601 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MAPTMAPK1POLBTDP1 | |
| SCHEMBL12691729 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MAPTMAPK1POLBRAB9A | |
| SCHEMBL12688302 | 0.76 | L3MBTL1 (0.36) | RXFP1L3MBTL1 | |
| SCHEMBL14768892 | 0.76 | ALDH1A1 (0.34) | ALDH1A1MAPTMAPK1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120245026-A1 | SPIRO FUSED 1-AMINO - PIPERDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-27 | — | — | US | disclosed |
| US-20120245026-A1 | SPIRO FUSED 1-AMINO - PIPERDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245026-A1 | SPIRO FUSED 1-AMINO - PIPERDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | DDT, CAT, AQP1 | ALDH1A1 79/4885MAPT 4292/4885MAPK1 2518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.