Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12688302 | 0.92 | L3MBTL1 (0.36) | RXFP1L3MBTL1 | |
| SCHEMBL1955250 | 0.89 | — | — | |
| SCHEMBL15424657 | 0.89 | L3MBTL1 (0.35) | RXFP1L3MBTL1 | |
| SCHEMBL1963200 | 0.88 | — | — | |
| SCHEMBL37429 | 0.86 | RXFP1 (0.35) | RXFP1L3MBTL1 | |
| SCHEMBL12688317 | 0.84 | ALDH1A1 (0.37) | RXFP1L3MBTL1 | |
| SCHEMBL12456817 | 0.84 | ALDH1A1 (0.35) | — | |
| SCHEMBL12688303 | 0.82 | FFAR4 (0.34) | L3MBTL1 | |
| SCHEMBL12573637 | 0.81 | HRH3 (0.31) | — | |
| SCHEMBL15032115 | 0.79 | RXFP1 (0.32) | RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703165-B2 | Spiro fused 1-amino-piperdine pyrrolidine dione derivatives with pesticidal activity | SYNGENTA CROP PROTECTION, INC. (US) | 2014-04-22 | — | — | US | disclosed |
| EP-2507240-B1 | SPIRO FUSED 1-AMINO-PIPERIDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-15 | — | — | EP | disclosed |
| EP-2507240-A1 | SPIRO FUSED 1 -AMINO - PIPERIDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | Syngenta Participations AG (CH) | 2012-10-10 | — | — | EP | disclosed |
| US-20120245026-A1 | SPIRO FUSED 1-AMINO - PIPERDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-27 | — | — | US | disclosed |
| US-20120245026-A1 | SPIRO FUSED 1-AMINO - PIPERDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-27 | — | — | US | disclosed |
| US-20120245026-A1 | SPIRO FUSED 1-AMINO - PIPERDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-27 | — | — | US | disclosed |
| WO-2011067240-A1 | SPIRO FUSED 1 -AMINO - PIPERIDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011067240-A1 | SPIRO FUSED 1 -AMINO - PIPERIDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011067135-A1 | SPIRO FUSED 1 -AMINO - PIPERIDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011067135-A1 | SPIRO FUSED 1 -AMINO - PIPERIDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245026-A1 | SPIRO FUSED 1-AMINO - PIPERDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | DDT, CAT, AQP1 | RXFP1 422/4885L3MBTL1 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.