Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17618927 | 0.85 | ALDH1A1 (0.57) | PTGS2CA1CA2CA12ALOX5 | |
| SCHEMBL13680103 | 0.85 | ALDH1A1 (0.56) | MEN1KMT2AKDM4EALDH1A1CYP2C9 | |
| SCHEMBL27709150 | 0.81 | CA12 (0.59) | PTGS2CA1CA2CA12CA7 | |
| SCHEMBL11742219 | 0.80 | PTGS2 (0.59) | PTGS2CA1CA2CA12ALOX5 | |
| SCHEMBL16263287 | 0.80 | LCK (0.41) | CA1CA2CA12CA7CA9 | |
| SCHEMBL12050828 | 0.80 | POLB (0.43) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL6279030 | 0.78 | KDM4E (0.46) | PTGS2CA1CA2CA12ALOX5 | |
| SCHEMBL29431885 | 0.77 | CA1 (0.61) | PTGS2CA1CA2CA12ALOX5 | |
| SCHEMBL128781 | 0.77 | CA1 (0.61) | PTGS2CA1CA2CA12ALOX5 | |
| SCHEMBL16263288 | 0.76 | LCK (0.44) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103249455-A | Process for dyeing keratin fibres using hydroxybenzaldehyde derivatives, oxidizing agents and alkalinizing agents in the presence of heat | OREAL | 2013-08-14 | — | — | CN | claimed |
| US-20170065547-A1 | Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Skin Cancer | ACTION MEDICINES, S.L. (ES) | 2017-03-09 | — | — | US | disclosed |
| US-20140018460-A1 | COMPOSITIONS FOR IMPROVING POLYESTERS | NEXAM CHEMICAL AB (SE) | 2014-01-16 | — | — | US | disclosed |
| CN-103249455-A | Process for dyeing keratin fibres using hydroxybenzaldehyde derivatives, oxidizing agents and alkalinizing agents in the presence of heat | OREAL | 2013-08-14 | — | — | CN | disclosed |
| CN-101212972-B | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility | ORGANON NV | 2011-06-08 | — | — | CN | disclosed |
| CN-101212972-A | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility | ORGANON NV (NL) | 2008-07-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170065547-A1 | Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Skin Cancer | CYP8B1, CYP26B1, CYP24A1 | PTGS2 1090/4885CA1 1782/4885CA2 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.