Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263288 | 0.86 | LCK (0.44) | LCKFYNALDH1A1HSD17B10TSHR | |
| SCHEMBL13680103 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL15425835 | 0.80 | PTGS2 (0.52) | LCKALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL12050828 | 0.79 | POLB (0.43) | ALDH1A1HSD17B10KDM4EPOLBTDP1 | |
| SCHEMBL227238 | 0.78 | SMN1; SMN2 (0.59) | LCKFYNALDH1A1HSD17B10MEN1 | |
| SCHEMBL23483729 | 0.77 | CFD (0.61) | ALDH1A1HSD17B10PKMTSHRKDM4E | |
| SCHEMBL10262241 | 0.77 | NPC1 (0.34) | ALDH1A1 | |
| SCHEMBL17618927 | 0.76 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL31485885 | 0.75 | TAS2R14 (0.49) | LCKFYNALDH1A1HSD17B10MEN1 | |
| SCHEMBL15958587 | 0.75 | HTT (0.44) | ALDH1A1KDM4EPOLBTDP1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701841-B2 | Cell permeable, fluorescent dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-07-11 | — | — | US | disclosed |
| US-20160230011-A1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-08-11 | — | — | US | disclosed |
| US-9346957-B2 | Cell permeable, fluorescent dye | ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) | 2016-05-24 | — | — | US | disclosed |
| US-20140349282-A1 | Cell Permeable, Fluorescent Dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160230011-A1 | CELL PERMEABLE, FLUORESCENT DYE | EPCAM, IK, TSPO | LCK 4074/4885FYN 3521/4885ALDH1A1 1077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.