SCHEMBL15426414

SCHEMBL15426414

CC[S+]([O-])c1ccccc1-c1nc2cc(C)cnc2s1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ CYP1A2 P05177 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.31
▸ AHR P35869 1/20 0.31
▸ KIT P10721 1/20 0.31
▸ THRB P10828 1/20 0.31
▸ F2RL3 Q96RI0 1/20 0.31
▸ NPC1 O15118 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ S1PR1 P21453 1/20 0.31
▸ S1PR3 Q99500 1/20 0.31
▸ GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11953205 0.86 ALDH1A1 (0.31) LMNAALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL10280796 0.84 S1PR1 (0.36) LMNAALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL15426371 0.81 MAPT (0.45) LMNAALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL13470780 0.77 SMN1; SMN2 (0.53) ALDH1A1HPGDSMN1; SMN2CYP1A2KDM4E
SCHEMBL15426418 0.76 ALOX5AP (0.39) LMNAALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL15426421 0.75 ALDH1A1 (0.42) LMNAALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL15426278 0.74 AKT1 (0.38) ALDH1A1HPGDCYP1A2KDM4EMAPT
SCHEMBL20708505 0.74 NPC1 (0.34) ALDH1A1HPGDHTTSMN1; SMN2CYP1A2
SCHEMBL15412909 0.74 BRD4 (0.38) LMNACYP1A2KDM4EMAPTGAA
SCHEMBL15426364 0.74 SGMS2 (0.38) ALDH1A1HPGDSMN1; SMN2CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278983-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-08 — — US disclosed
US-20150148308-A1 PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-28 — — US disclosed
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-11 — — US disclosed
US-8853238-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-07 — — US disclosed
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF NR4A1, NR2C2, NR0B1 LMNA 1591/4885ALDH1A1 3178/4885HPGD 4315/4885
US-20150148308-A1 PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS SFXN1, OSR1, PIR LMNA 3171/4885ALDH1A1 2709/4885HPGD 4672/4885
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL NR4A1, NR2C2, NR0B1 LMNA 1629/4885ALDH1A1 3047/4885HPGD 4230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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