Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16372409 | 0.86 | SMN1; SMN2 (0.37) | POLBMAPK1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL21261476 | 0.83 | ALDH1A1 (0.36) | POLBMAPK1RAB9AGBA1MAPT | |
| SCHEMBL18977545 | 0.74 | SCN1A (0.42) | POLBMAPT | |
| SCHEMBL15426481 | 0.74 | L3MBTL1 (0.44) | EGFRSMN1; SMN2RAB9AMAPT | |
| SCHEMBL12814024 | 0.73 | RAB9A (0.54) | POLBMAPK1ALOX12SMN1; SMN2RAB9A | |
| SCHEMBL12814019 | 0.73 | RAB9A (0.54) | POLBMAPK1ALOX12SMN1; SMN2RAB9A | |
| SCHEMBL9792253 | 0.72 | NPC1 (0.56) | POLBEGFRSMN1; SMN2RAB9AMAPT | |
| SCHEMBL21253061 | 0.71 | MAPK1 (0.35) | POLBMAPK1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL17853431 | 0.71 | ALDH1A1 (0.35) | MAPK1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL20684265 | 0.71 | NR4A2 (0.45) | POLBEGFRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019493-B1 | MODIFIED BET-PROTEIN INHIBITING DIHYDROCHINOXALINONES AND DIHYDROPYRIDOPYRAZINONES | Bayer Pharma AG (DE) | 2017-06-14 | — | — | EP | disclosed |