Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ11 | Q14654 | 9/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 7/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 7/20 | 0.42 |
| ▸ | KCNJ8 | Q15842 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2892422 | 0.83 | ABCC9 (0.55) | KCNJ11ABCC9ABCC8KCNJ8MEN1 | |
| SCHEMBL7539767 | 0.80 | GAA (0.53) | KCNJ11ABCC9ABCC8KCNJ8MEN1 | |
| SCHEMBL15427833 | 0.77 | KDM4E (0.49) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL21320132 | 0.76 | ERN1 (0.42) | MEN1KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL16381880 | 0.76 | ERN1 (0.46) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL15428050 | 0.76 | L3MBTL1 (0.42) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL2975369 | 0.73 | ERN1 (0.46) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15565974 | 0.73 | CETP (0.47) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL12513036 | 0.73 | PDK1 (0.51) | MEN1KMT2AL3MBTL1LMNAMAPT | |
| SCHEMBL30621465 | 0.73 | ERN1 (0.46) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9837622-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-9837622-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-20150263297-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| US-20150263297-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| WO-2014008982-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150263297-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | KCNJ11 352/4885ABCC9 2543/4885ABCC8 3995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.