Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.60 |
| ▸ | HTR1D | P28221 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.60 |
| ▸ | HTR3A | P46098 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | SPR | P35270 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16923032 | 0.87 | EGFR (0.52) | HTR6HTR1DHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL16716149 | 0.84 | HTR1D (0.61) | HTR6HTR1DHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL4292563 | 0.83 | HTR6 (0.62) | HTR6HTR1DHSD17B10CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL16711692 | 0.83 | HTR1D (0.60) | HTR6HTR1DHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL16711712 | 0.80 | SPR (0.47) | HSD17B10CYP1A2CYP3A4CYP2D6NPSR1 | |
| SCHEMBL18235616 | 0.80 | TRPM8 (0.66) | HTR6HSD17B10CYP1A2CYP2C9NPSR1 | |
| Hydrochloric Acid SCHEMBL18222557 | 0.79 | TRPM8 (0.65) | HTR6HSD17B10CYP1A2CYP2C9NPSR1 | |
| SCHEMBL16923054 | 0.78 | HTR6 (0.41) | HTR6HTR1DHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL29361176 | 0.76 | HTR6 (1.00) | HTR6HTR1DHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL399028 | 0.76 | HTR6 (1.00) | HTR6HTR1DHSD17B10CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014010602-A1 | INDOLECARBOXAMIDE DERIVATIVE | アステラス製薬株式会社 (JP) | 2014-01-16 | — | — | WO | disclosed |