Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.62 |
| ▸ | HTR1D | P28221 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | HTR7 | P34969 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | HTR3A | P46098 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427985 | 0.83 | HTR6 (0.60) | HTR6HTR1DCYP1A2HTR7HSD17B10 | |
| SCHEMBL5495499 | 0.80 | HTR6 (0.66) | HTR6HTR1DHTR7HTR1AHTR1B | |
| SCHEMBL5066580 | 0.80 | NPSR1 (0.44) | HTR6HTR1DCYP1A2HTR7HSD17B10 | |
| SCHEMBL29361176 | 0.77 | HTR6 (1.00) | HTR6HTR1DCYP1A2HTR7HSD17B10 | |
| SCHEMBL399028 | 0.77 | HTR6 (1.00) | HTR6HTR1DCYP1A2HTR7HSD17B10 | |
| SCHEMBL14481047 | 0.77 | HTR1D (0.62) | HTR6HTR1DCYP1A2HTR7HSD17B10 | |
| Hydrochloric Acid SCHEMBL5791576 | 0.76 | HTR6 (0.97) | HTR6HTR1DCYP1A2HTR7HSD17B10 | |
| SCHEMBL4434210 | 0.75 | HTR6 (0.44) | HTR6HTR1DCYP1A2HTR7HSD17B10 | |
| SCHEMBL26989650 | 0.75 | HTR6 (0.68) | HTR6HTR1DCYP1A2HTR7HSD17B10 | |
| Fumaric Acid SCHEMBL1320838 | 0.74 | NPSR1 (1.00) | HTR6HTR1DCYP1A2HTR7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140228543-A1 | MODIFIED AND DERIVATIZED ß-GLUCAN COMPOUNDS, COMPOSITIONS, AND METHODS | MIDCAP FINANCIAL TRUST, AS AGENT | 2014-08-14 | — | — | US | disclosed |
| WO-2012154680-A2 | MODIFIED AND DERIVATIZED β-GLUCAN COMPOUNDS, COMPOSITIONS, AND METHODS | BIOTHERA, INC. (US) | 2012-11-15 | — | — | WO | disclosed |
| US-8309576-B2 | Method of treating inflammatory bowel disease | AJINOMOTO CO., INC. (JP) | 2012-11-13 | — | — | US | disclosed |
| US-8080564-B2 | Hemodynamics improving agent | AJINOMOTO CO., INC. (JP) | 2011-12-20 | — | — | US | disclosed |
| US-20090156657-A1 | ANTI-INFLAMMATORY COMPOSITION | AJINOMOTO CO., INC. (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20080171781-A1 | HEMODYNAMICS IMPROVING AGENT | AJINOMOTO CO., INC. (JP) | 2008-07-17 | — | — | US | disclosed |
| EP-1935419-A1 | HEMODYNAMICS IMPROVING AGENT | Ajinomoto Co., Inc. (JP) | 2008-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228543-A1 | MODIFIED AND DERIVATIZED ß-GLUCAN COMPOUNDS, COMPOSITIONS, AND METHODS | MANBA, ALG1, MAN2A1 | HTR6 4375/4885HTR1D 3796/4885CYP1A2 2209/4885 |
| US-20090156657-A1 | ANTI-INFLAMMATORY COMPOSITION | VCAM1, ICAM1, TPH1 | HTR6 11/4885HTR1D 19/4885CYP1A2 1111/4885 |
| US-20080171781-A1 | HEMODYNAMICS IMPROVING AGENT | TPH1, HTR1A, VASP | HTR6 4/4885HTR1D 17/4885CYP1A2 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.