Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 9/20 | 0.52 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.52 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318017 | 0.81 | WDR5 (0.53) | ALDH1A1USP2HPGDMMP13ERCC1 | |
| SCHEMBL1316829 | 0.80 | MMP13 (0.65) | MMP13 | |
| SCHEMBL7920065 | 0.78 | MMP13 (0.84) | MMP13 | |
| SCHEMBL1317016 | 0.78 | MMP13 (0.84) | MMP13 | |
| SCHEMBL1318756 | 0.77 | NR1H4 (0.55) | ALDH1A1HPGDMMP13ERCC1ERCC4 | |
| SCHEMBL507837 | 0.76 | ALDH1A1 (0.90) | ALDH1A1USP2HPGDERCC1ERCC4 | |
| SCHEMBL6244724 | 0.74 | ALDH1A1 (0.93) | ALDH1A1USP2HPGDERCC1ERCC4 | |
| SCHEMBL13039162 | 0.74 | SMN1; SMN2 (0.64) | ALDH1A1USP2HPGDERCC1ERCC4 | |
| SCHEMBL5523329 | 0.74 | ALDH1A1 (0.61) | ALDH1A1USP2HPGDERCC1ERCC4 | |
| SCHEMBL14724835 | 0.74 | ALDH1A1 (0.61) | ALDH1A1USP2HPGDERCC1ERCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637550-B2 | Heteroaryl diamide compounds useful as MMP-13 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-28 | — | — | US | disclosed |