SCHEMBL15433835

SCHEMBL15433835

CCC/C(F)=C(\F)c1ccc(-c2ccc(-c3cc(F)c(-c4cc(F)c(-c5cc(F)c(C(F)(F)F)c(F)c5)c(F)c4)c(F)c3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.36
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433500 0.94 RARB (0.34) KIF11
SCHEMBL15433575 0.92 DAO (0.34) KIF11
SCHEMBL15433428 0.87 KIF11 (0.37) KIF11HPGDSMN1; SMN2L3MBTL1
SCHEMBL15433211 0.86 KIF11 (0.38) KIF11RXRARXRBRXRG
SCHEMBL15433498 0.82 RARB (0.41) KIF11
SCHEMBL15433651 0.80 KIF11 (0.36) KIF11
SCHEMBL15433577 0.80 RARB (0.35)
SCHEMBL15433788 0.80
SCHEMBL15433212 0.79 KIF11 (0.36) KIF11RXRARXRBRXRG
SCHEMBL15433789 0.79 RORC (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed