SCHEMBL15433211

SCHEMBL15433211

CCCC/C(F)=C(\F)c1ccc(-c2ccc(-c3cc(F)c(C(F)(F)F)c(F)c3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.38
MGLL Q99685 7/20 0.36
HTR7 P34969 1/20 0.36
RARB P10826 3/20 0.34
RARA P10276 1/20 0.34
RARG P13631 1/20 0.34
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
RORC P51449 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
LTB4R2 Q9NPC1 2/20 0.32
FAAH O00519 2/20 0.32
CNR1 P21554 2/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433835 0.86 KIF11 (0.36) KIF11RXRARXRBRXRG
SCHEMBL15433260 0.85 RARB (0.37) KIF11RARBRARARARGLTB4R2
SCHEMBL15433359 0.85 S1PR1 (0.37) KIF11MGLLRARBRARARARG
SCHEMBL15433428 0.84 KIF11 (0.37) KIF11RARBRORC
SCHEMBL15433651 0.82 KIF11 (0.36) KIF11
SCHEMBL15433350 0.82 KIF11 (0.37) KIF11MGLLRARBRARARARG
SCHEMBL15433500 0.81 RARB (0.34) KIF11RARBRARARARG
SCHEMBL15433212 0.81 KIF11 (0.36) KIF11RXRARXRBRXRG
SCHEMBL15433789 0.81 RORC (0.31) RORC
SCHEMBL7231325 0.81 HTR7 (0.54) HTR7RARBHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed