SCHEMBL10111002

SCHEMBL10111002

Cc1ccc2c(c1)C(C(=O)O)c1cc(C)c3ccccc3c1-2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 2/20 0.36
LMNA P02545 2/20 0.36
ALDH1A1 P00352 5/20 0.34
HTT P42858 2/20 0.34
TP53 P04637 1/20 0.34
NTRK1 P04629 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 3/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
CYP1A2 P05177 1/20 0.33
GFER P55789 1/20 0.33
NPC1 O15118 1/20 0.33
ELANE P08246 1/20 0.33
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
USP2 O75604 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1815795 0.81 LDHA (0.36) ALDH1A1HTTPOLBKMT2AHPGD
SCHEMBL9449550 0.78 ESR1 (0.40) LMNAALDH1A1POLBKMT2AHPGD
SCHEMBL9449539 0.77 HDAC3 (0.44) LMNAALDH1A1POLBKMT2AHPGD
SCHEMBL10111005 0.77 ALDH1A1 (0.37) GRM2LMNAALDH1A1HTTTP53
SCHEMBL15435550 0.77 CYP1A2 (0.33) GRM2ALDH1A1NTRK1KMT2AHPGD
SCHEMBL10111189 0.74 GPR3 (0.40) ALDH1A1KMT2AHPGDHSD17B10KDM4E
SCHEMBL20169172 0.73 LMNA (0.44) LMNAALDH1A1POLBKMT2AMEN1
SCHEMBL15435551 0.71 KMT2A (0.33) ALDH1A1NTRK1KMT2AHPGDHSD17B10
SCHEMBL1067272 0.71 THRB (0.40) LMNAHTTTP53POLBKMT2A
SCHEMBL10111193 0.69 KDM1A (0.34) ALDH1A1TP53KMT2AHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9536633-B2 Metallic composite and composition thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-01-03 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
EP-2478981-A1 SILVER-(CONJUGATED COMPOUND) COMPLEX Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF CDH1, EPCAM, CD4 GRM2 861/4885LMNA 2625/4885ALDH1A1 932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.