Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435944 | 0.86 | HTR1A (0.35) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL15435914 | 0.85 | HRH3 (0.34) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL16898773 | 0.80 | MEN1 (0.32) | MEN1KMT2AKDM4EHRH3 | |
| SCHEMBL15435928 | 0.77 | MEN1 (0.51) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL1525497 | 0.76 | CYP2J2 (0.33) | MEN1KMT2AHRH1SIGMAR1 | |
| SCHEMBL2076961 | 0.76 | MAPK1 (0.37) | KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL15435926 | 0.75 | MEN1 (0.39) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL3657529 | 0.75 | CYP2J2 (0.32) | HRH1 | |
| SCHEMBL28780771 | 0.75 | DRD3 (0.33) | SMN1; SMN2SIGMAR1 | |
| SCHEMBL3009489 | 0.75 | CYP2J2 (0.32) | HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014016202-A1 | METHODS FOR CATALYTIC ALKYLATION OF NUCLEIC ACIDS | UNIVERSITÄT BASEL (CH) | 2014-01-30 | — | — | WO | disclosed |
| EP-2689847-A1 | Methods for catalytic alkylation of nucleic acids | Universität Basel (CH) | 2014-01-29 | — | — | EP | disclosed |