Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16898833 | 0.82 | KCNA5 (0.46) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL15435944 | 0.78 | HTR1A (0.35) | MEN1KMT2AHRH2HRH1CYP2D6 | |
| SCHEMBL15435914 | 0.77 | HRH3 (0.34) | MEN1KMT2ACYP2D6GAAALDH1A1 | |
| SCHEMBL15435917 | 0.75 | MEN1 (0.44) | MEN1KMT2AHRH2HRH1GAA | |
| SCHEMBL15435927 | 0.75 | KMT2A (0.49) | MEN1KMT2AMMP13 | |
| SCHEMBL16906911 | 0.75 | KMT2A (0.49) | MEN1KMT2AMMP13 | |
| SCHEMBL26101702 | 0.73 | HRH3 (0.41) | CYP2J2KDM4EHRH3 | |
| SCHEMBL16898356 | 0.72 | ALDH1A1 (0.41) | MEN1KMT2ACYP2D6ALDH1A1KDM4E | |
| SCHEMBL634557 | 0.72 | ALDH1A1 (0.39) | MEN1KMT2ACYP2D6GAATSHR | |
| SCHEMBL16728454 | 0.72 | L3MBTL1 (0.40) | KMT2ACYP2D6MMP9MMP13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014016202-A1 | METHODS FOR CATALYTIC ALKYLATION OF NUCLEIC ACIDS | UNIVERSITÄT BASEL (CH) | 2014-01-30 | — | — | WO | disclosed |
| EP-2689847-A1 | Methods for catalytic alkylation of nucleic acids | Universität Basel (CH) | 2014-01-29 | — | — | EP | disclosed |