Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.67 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.67 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.67 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.67 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.67 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.67 |
| ▸ | GABRP | O00591 | 3/20 | 0.67 |
| ▸ | GABRD | O14764 | 3/20 | 0.67 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.67 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.67 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.67 |
| ▸ | GABRE | P78334 | 3/20 | 0.67 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.67 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.67 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.67 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.67 |
| ▸ | CDK4 | P11802 | 2/20 | 0.54 |
| ▸ | CCND1 | P24385 | 2/20 | 0.54 |
| ▸ | TDO2 | P48775 | 3/20 | 0.49 |
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410201 | 0.82 | PARP1 (0.60) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29559082 | 0.82 | PARP1 (0.60) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9145 | 0.82 | PARP1 (0.60) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29381361 | 0.81 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL224017 | 0.81 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Hydrochloric Acid SCHEMBL2770160 | 0.81 | PARP1 (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Carbazole SCHEMBL143086 | 0.81 | ALDH1A1 (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28982242 | 0.81 | PARP1 (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Carbazole SCHEMBL28956846 | 0.81 | ALDH1A1 (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL23099057 | 0.78 | KIF11 (0.56) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687530-B1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE | NIPPON STEEL & SUMIKIN CHEM CO (JP) | 2018-07-11 | — | — | EP | disclosed |
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| EP-2687530-A1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS | Nippon Steel & Sumikin Chemical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |