Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | USP8 | P40818 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15444620 | 0.80 | CYP1A2 (0.51) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL7682175 | 0.75 | ALDH1A1 (0.55) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL13860655 | 0.75 | NPC1 (0.54) | ALDH1A1L3MBTL1USP8MEN1KMT2A | |
| SCHEMBL15438863 | 0.73 | PDE10A (0.48) | ALDH1A1MEN1KMT2AMAPT | |
| Benzoic Acid SCHEMBL28158909 | 0.73 | IRAK1 (0.51) | ALDH1A1L3MBTL1KDM4EMAPTNPC1 | |
| SCHEMBL15070241 | 0.73 | USP8 (0.77) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL2730578 | 0.71 | RAB9A (0.63) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL2690530 | 0.71 | USP8 (0.55) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL14133059 | 0.70 | USP8 (0.72) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL15440111 | 0.69 | AOC3 (0.41) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180029995-A1 | PYRIDAZINONE AND PYRIDONE COMPOUNDS | BIOTIE THERAPIES CORPORATION (FI) | 2018-02-01 | — | — | US | disclosed |
| US-9815795-B2 | Pyridazinone and pyridone compounds | BIOTIE THERAPIES CORPORATION (FI) | 2017-11-14 | — | — | US | disclosed |
| US-20160244414-A1 | PYRIDAZINONE AND PYRIDONE COMPOUNDS | BIOTIE THERAPIES CORPORATION (FI) | 2016-08-25 | — | — | US | disclosed |
| US-9371290-B2 | Pyridazinone compounds | BIOTIE THERAPIES CORPORATION (FI) | 2016-06-21 | — | — | US | disclosed |
| US-20140024648-A1 | NEW PYRIDAZINONE AND PYRIDONE COMPOUNDS | BIOTIE THERAPIES CORPORATION (FI) | 2014-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244414-A1 | PYRIDAZINONE AND PYRIDONE COMPOUNDS | XDH, PNPO, PDXK | CA1 3572/4885CA2 2759/4885CA12 4631/4885 |
| US-20140024648-A1 | NEW PYRIDAZINONE AND PYRIDONE COMPOUNDS | XDH, PNPO, PDXK | CA1 3791/4885CA2 2828/4885CA12 4723/4885 |
| US-20180029995-A1 | PYRIDAZINONE AND PYRIDONE COMPOUNDS | XDH, PNPO, PDXK | CA1 3572/4885CA2 2759/4885CA12 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.