Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP8 | P40818 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652545 | 0.86 | ADORA3 (0.49) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL7679154 | 0.80 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| Dimethylamine SCHEMBL7679157 | 0.79 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7658278 | 0.79 | MAPT (0.52) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7657325 | 0.79 | ADORA3 (0.54) | ALDH1A1MAPTADORA3 | |
| SCHEMBL7652943 | 0.75 | RPA1 (0.52) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL15438873 | 0.75 | CA1 (0.49) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7649140 | 0.74 | TP53 (0.58) | ALDH1A1L3MBTL1MAPTKDM4ERAB9A | |
| SCHEMBL7650590 | 0.74 | KDM4E (0.49) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7656778 | 0.74 | HIF1A (0.49) | ALDH1A1MAPTKDM4EADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |