SCHEMBL15438962

SCHEMBL15438962

C[SiH](C)N(Cc1ccccc1)N=C1C(=O)C(Cl)=C(Cl)C(Cl)=C1Cl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DEPTOR Q8TB45 1/20 0.35
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
CA2 P00918 1/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
TAS2R14 Q9NYV8 3/20 0.32
TMEM97 Q5BJF2 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
LRRK2 Q5S007 1/20 0.32
AOC3 Q16853 1/20 0.32
CXCR3 P49682 1/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15439780 0.80 G6PC1 (0.41) DEPTORALDH1A1TSHRCA2LRRK2
SCHEMBL15439797 0.77 DEPTOR (0.35) DEPTORALDH1A1TSHRCA2MEN1
SCHEMBL15440541 0.75 DEPTOR (0.37) DEPTORALDH1A1MEN1KMT2ALRRK2
SCHEMBL15439742 0.72 ALDH1A1 (0.36) ALDH1A1TSHRCA2MEN1KMT2A
SCHEMBL15438795 0.71 G6PC1 (0.40) ALDH1A1TSHRCA2KMT2ALRRK2
SCHEMBL15439867 0.71 NPC1 (0.36) ALDH1A1TSHRCA2MEN1KMT2A
SCHEMBL15439732 0.71 ALDH1A1 (0.35) ALDH1A1TSHRCA2AOC3NPC1
SCHEMBL15439801 0.71 NPC1 (0.36) ALDH1A1TSHRCA2MEN1KMT2A
SCHEMBL15439609 0.70 TSHR (0.34) ALDH1A1TSHRCA2KMT2ALRRK2
SCHEMBL15440232 0.69 G6PC1 (0.41) ALDH1A1TSHRCA2KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115231-B2 Polymers functionalized with protected hydrazone compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2015-08-25 US disclosed
US-20140031488-A1 Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed