Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439882 | 0.88 | PIK3CA (0.48) | XDHCNR1PTGER1DHODHHPGD | |
| SCHEMBL15440078 | 0.87 | CDH1 (0.42) | CNR1DHODHCTRC | |
| SCHEMBL15449338 | 0.84 | CNR1 (0.42) | CNR1DHODHHPGDALDH1A1KDM4E | |
| SCHEMBL15449337 | 0.81 | MAP2K4 (0.39) | CNR1ACMSD | |
| SCHEMBL15440025 | 0.80 | CNR1 (0.44) | CNR1DHODHHPGDALDH1A1KDM4E | |
| SCHEMBL15439887 | 0.78 | PDCD1 (0.50) | HPGDALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL15439892 | 0.77 | CDH1 (0.49) | CNR1PTGER1DHODHSMN1; SMN2CTRC | |
| SCHEMBL15449707 | 0.74 | KMO (0.48) | CNR1DHODHHPGDALDH1A1KDM4E | |
| SCHEMBL19267254 | 0.73 | CNR2 (0.36) | CNR1PTGER1NPC1RAB9ACNR2 | |
| SCHEMBL27754847 | 0.72 | GRM2 (0.47) | HPGDALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877452-B1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2017-08-23 | — | — | EP | disclosed |
| EP-2877452-B1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2017-08-23 | — | — | EP | disclosed |
| CN-104640844-B | The preparation method of 4-amino-5-fluorine-3-halo-6-(substituted) pyridine-2-formic acid esters | 美国陶氏益农公司 | 2016-11-09 | — | — | CN | disclosed |
| EP-2877453-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2016-07-06 | — | — | EP | disclosed |
| EP-2877453-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2016-07-06 | — | — | EP | disclosed |
| US-9376388-B2 | Fluoropicolinoyl fluorides and processes for their preparation | DOW AGROSCIENCES LLC (US) | 2016-06-28 | — | — | US | disclosed |
| US-9376388-B2 | Fluoropicolinoyl fluorides and processes for their preparation | DOW AGROSCIENCES LLC (US) | 2016-06-28 | — | — | US | disclosed |
| US-9376388-B2 | Fluoropicolinoyl fluorides and processes for their preparation | DOW AGROSCIENCES LLC (US) | 2016-06-28 | — | — | US | disclosed |
| US-20150191428-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | CORTEVA AGRISCIENCE LLC | 2015-07-09 | — | — | US | disclosed |
| US-20150191428-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | CORTEVA AGRISCIENCE LLC | 2015-07-09 | — | — | US | disclosed |
| US-8871943-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-10-28 | — | — | US | disclosed |
| US-8871943-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140031558-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031558-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| WO-2014018502-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | WO | disclosed |
| US-20140031558-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| WO-2014018506-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | CLIC4, NPEPPS, CYP4F3 | XDH 2964/4885CNR1 2685/4885PTGER1 4856/4885 |
| US-20150191428-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | FLI1, ABL1, FLNA | XDH 3518/4885CNR1 2463/4885PTGER1 4841/4885 |
| US-20140031558-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | FLI1, ABL1, FLNA | XDH 3518/4885CNR1 2463/4885PTGER1 4841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.