Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.31 |
| ▸ | MMP9 | P14780 | 3/20 | 0.31 |
| ▸ | MMP8 | P22894 | 3/20 | 0.31 |
| ▸ | MMP13 | P45452 | 3/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445150 | 0.77 | DPP4 (0.39) | NOTUMP2RX7DPP4 | |
| SCHEMBL20216912 | 0.76 | DGAT1 (0.39) | HSP90AB1DGAT1NOTUMNCF1ALOX5 | |
| SCHEMBL22384825 | 0.74 | DGAT1 (0.33) | HSP90AB1DGAT1P2RX7MMP2MMP9 | |
| SCHEMBL22380843 | 0.72 | — | — | |
| SCHEMBL19576264 | 0.71 | NOTUM (0.39) | NOTUMP2RX7MMP2MMP9MMP8 | |
| SCHEMBL15445151 | 0.71 | P2RX7 (0.36) | HSP90AB1DGAT1P2RX7 | |
| SCHEMBL24372151 | 0.70 | NCF1 (0.43) | HSP90AB1DGAT1NCF1ABCC1ABCG2 | |
| SCHEMBL26846503 | 0.70 | ALOX5 (0.32) | HSP90AB1ALOX5 | |
| SCHEMBL1170302 | 0.69 | — | — | |
| SCHEMBL19576265 | 0.69 | NOTUM (0.39) | NOTUMP2RX7DPP4LGALS3NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2690105-A1 | Mannose derivatives, a process for preparing the same and their uses as a drug | Centre National De La Recherche Scientifique (FR) | 2014-01-29 | — | — | EP | disclosed |