SCHEMBL15449484

SCHEMBL15449484

C[C@@H]1C(COS(=O)(=O)O)OC(O)C(NS(=O)(=O)O)[C@@H]1O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 2/20 0.36
▸ AMDHD2 Q9Y303 1/20 0.33
▸ CA2 P00918 1/20 0.32
▸ F2 P00734 1/20 0.32
▸ SERPINC1 P01008 1/20 0.32
▸ FGF1 P05230 1/20 0.31
▸ FGF2 P09038 1/20 0.31
▸ SMPD1 P17405 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20987120 0.87 F10 (0.42) F10AMDHD2CA2F2SERPINC1
SCHEMBL13286928 0.87 F10 (0.42) F10AMDHD2CA2F2SERPINC1
SCHEMBL7209918 0.87 F10 (0.42) F10AMDHD2CA2F2SERPINC1
SCHEMBL16728926 0.87 F10 (0.42) F10AMDHD2CA2F2SERPINC1
SCHEMBL7209912 0.87 F10 (0.42) F10AMDHD2CA2F2SERPINC1
SCHEMBL1009127 0.87 F10 (0.42) F10AMDHD2CA2F2SERPINC1
SCHEMBL21067663 0.87 F10 (0.42) F10AMDHD2CA2F2SERPINC1
SCHEMBL29535532 0.82 F10 (0.48) F10F2SERPINC1FGF1FGF2
SCHEMBL29534894 0.79 F10 (0.43) F10AMDHD2CA2F2SERPINC1
SCHEMBL16729027 0.77 F10 (0.41) F10F2SERPINC1FGF1FGF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9346894-B2 Polysaccharides comprising two antithrombin III-binding sites, preparation thereof and use thereof as antithrombotic medicaments SANOFI (FR) 2016-05-24 — — US disclosed
US-20140031316-A1 POLYSACCHARIDES COMPRISING TWO ANTITHROMBIN III-BINDING SITES, PREPARATION THEREOF AND USE THEREOF AS ANTITHROMBOTIC MEDICAMENTS SANOFI (FR) 2014-01-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140031316-A1 POLYSACCHARIDES COMPRISING TWO ANTITHROMBIN III-BINDING SITES, PREPARATION THEREOF AND USE THEREOF AS ANTITHROMBOTIC MEDICAMENTS SERPINC1, F13B, F12 F10 16/4885AMDHD2 1295/4885CA2 1641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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