Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2349389 | 1.00 | TSHR (0.52) | TSHRLMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL1546681 | 1.00 | TSHR (0.52) | TSHRLMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL29246794 | 0.88 | CTSS (0.44) | TSHRLMNAKDM4EL3MBTL1PBRM1 | |
| SCHEMBL8902506 | 0.83 | CTSK (0.48) | TSHRLMNA | |
| SCHEMBL2207500 | 0.79 | SGMS2 (0.40) | LMNAAOC3PBRM1 | |
| SCHEMBL4169733 | 0.79 | LMNA (0.54) | TSHRLMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL23209157 | 0.78 | AOC3 (0.47) | TSHRLMNAL3MBTL1AOC3NPC1 | |
| SCHEMBL23237367 | 0.78 | AOC3 (0.47) | LMNAKDM4EAOC3 | |
| SCHEMBL4977775 | 0.78 | ESR1 (0.42) | LMNAKDM4ENPC1RAB9A | |
| SCHEMBL23237307 | 0.78 | ESR1 (0.42) | LMNAKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574049-A | Novel method for preparing phenylglycine by using hydrocyanic acid | 华阳新材料科技集团有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-108997122-B | 3-aryl-4-alkoxy benzyl ether derivative and preparation method and application thereof | 南方医科大学 | 2020-12-29 | — | — | CN | claimed |
| US-20130149769-A1 | NOVEL CARBONYL REDUCTASE, GENE THEREFOR AND USE THEREOF | KANEKA CORPORATION (JP) | 2013-06-13 | — | — | US | claimed |
| US-8008461-B2 | Carbonyl reductase, gene therefor and use thereof | KANEKA CORPORATION (JP) | 2011-08-30 | — | — | US | claimed |
| US-20090029430-A1 | Novel Carbonyl Reductase, Gene Therefor and Use Thereof | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | claimed |
| EP-1811021-A1 | NOVEL CARBONYL REDUCTASE, GENE THEREFOR AND USE THEREOF | Kaneka Corporation (JP) | 2007-07-25 | — | — | EP | claimed |
| US-7091011-B2 | 3-hydroxycarboxylic acid production and use in branched polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-08-15 | — | — | US | claimed |
| US-20030170837-A1 | 3-hydroxycarboxylic acid production and use in branched polymers | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2003-09-11 | — | — | US | claimed |
| US-20030166180-A1 | 3-Hydroxycarboxylic acid production and use in branched polymers | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2003-09-04 | — | — | US | claimed |
| EP-1309715-A2 | 3-HYDROXYCARBOXYLIC ACID PRODUCTION AND USE IN BRANCHED POLYMERS | E.I. Dupont de Nemours and Company (US) | 2003-05-14 | — | — | EP | claimed |
| US-6562603-B2 | Forming hydroxy group containing acid from hydroxy groupcontaining nitrile; polylactones | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-05-13 | — | — | US | claimed |
| WO-2002057475-A1 | STEREOSELECTIVE PREPARATION OF 3-HYDROXY-3-PHENYLPROPIONITRILE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-07-25 | — | — | WO | claimed |
| US-20020039770-A1 | 3-Hydroxycarboxylic acid production and use in branched polymers | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2002-04-04 | — | — | US | claimed |
| WO-2002012530-A2 | 3-HYDROXYCARBOXYLIC ACID PRODUCTION AND USE IN BRANCHED POLYMERS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2002-02-14 | — | — | WO | claimed |
| JP-5078302-A | — | — | None | — | — | JP | disclosed |
| JP-5092946-A | — | — | None | — | — | JP | disclosed |
| US-20230390401-A1 | RAPIDLY RELEASED BIOORTHOGONAL CAGING GROUPS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2023-12-07 | — | — | US | disclosed |
| US-4246189-A | FOR EASE OF MATERIALS HANDLING | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-01-20 | — | — | US | disclosed |
| US-4242489-A | Process for preparing polyurethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |
| US-4173567-A | Isocyanate derivatives of 1,3[oxazoles, oxazines, diazoles and diazines] | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029430-A1 | Novel Carbonyl Reductase, Gene Therefor and Use Thereof | AKR1C4, CBR3, FAR1 | TSHR 4560/4885LMNA 4135/4885KDM4E 2679/4885 |
| US-20230390401-A1 | RAPIDLY RELEASED BIOORTHOGONAL CAGING GROUPS | CBR3, CBR1, OR10J3 | TSHR 58/4885LMNA 4638/4885KDM4E 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.