SCHEMBL15467671

SCHEMBL15467671

C1=CC2CC1CC2COC1CC2CCC1C2

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
GAA P10253 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 2/20 0.33
CYP19A1 P11511 1/20 0.31
EPHX2 P34913 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1089463 0.74 CYP19A1 (0.44) ALDH1A1GAATDP1KDM4ECYP19A1
SCHEMBL15467915 0.73 ALDH1A1 (0.43) ALDH1A1GAATDP1KDM4EEPHX2
SCHEMBL20798696 0.73 ALDH1A1 (0.40) ALDH1A1GAATDP1CYP19A1EPHX2
SCHEMBL15466445 0.73 ALDH1A1 (0.40) ALDH1A1GAATDP1CYP19A1EPHX2
SCHEMBL1088620 0.73 ALDH1A1 (0.39) ALDH1A1GAATDP1KDM4EEPHX2
SCHEMBL1088893 0.72 ALDH1A1 (0.44) ALDH1A1GAATDP1KDM4E
SCHEMBL4741777 0.71 KDM4E (0.38) ALDH1A1KDM4ETSHR
SCHEMBL23619098 0.71 ALDH1A1 (0.39) ALDH1A1GAATDP1KDM4E
SCHEMBL22263738 0.71 ALDH1A1 (0.39) ALDH1A1GAATDP1KDM4ECYP19A1
SCHEMBL11735013 0.70 KDM4E (0.37) ALDH1A1KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10227433-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2019-03-12 US disclosed
US-10227433-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2019-03-12 US disclosed
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2016-12-22 US disclosed
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2016-12-22 US disclosed
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2016-12-22 US disclosed
US-9468890-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2016-10-18 US disclosed
US-9468890-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2016-10-18 US disclosed
US-9468890-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2016-10-18 US disclosed
EP-2870129-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION Promerus, LLC (US) 2015-05-13 EP disclosed
US-20140042090-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 US disclosed
US-20140042090-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 US disclosed
US-20140042090-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 US disclosed
WO-2014025735-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 WO disclosed
WO-2014025735-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION NOTUM, AGPS, WEE1 ALDH1A1 3394/4885GAA 2851/4885TDP1 2684/4885
US-10227433-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation NOTUM, AGPS, WEE1 ALDH1A1 3394/4885GAA 2851/4885TDP1 2684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.