Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDH1 | P40925 | 2/20 | 0.60 |
| ▸ | MDH2 | P40926 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.59 |
| ▸ | MLYCD | O95822 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31303632 | 0.87 | HIF1A (0.81) | MDH1MDH2HIF1AEPAS1SMN1; SMN2 | |
| SCHEMBL2957387 | 0.87 | HIF1A (0.81) | MDH1MDH2HIF1AEPAS1SMN1; SMN2 | |
| SCHEMBL8795261 | 0.85 | MDH1 (0.51) | MDH1MDH2HIF1AEPAS1MLYCD | |
| SCHEMBL9340133 | 0.81 | SMN1; SMN2 (0.61) | HIF1AEPAS1SMN1; SMN2NPC1MAPK1 | |
| SCHEMBL3498895 | 0.81 | LMNA (0.78) | MLYCDSMN1; SMN2LMNANPC1MAPK1 | |
| SCHEMBL1834517 | 0.81 | RAB9A (0.65) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL19134267 | 0.80 | HIF1A (0.72) | HIF1AEPAS1MLYCDSMN1; SMN2LMNA | |
| SCHEMBL31503974 | 0.80 | TRPV1 (0.70) | MDH1MDH2HIF1AEPAS1SMN1; SMN2 | |
| SCHEMBL7513074 | 0.80 | KMT2A (0.75) | HIF1AEPAS1SMN1; SMN2LMNANPC1 | |
| SCHEMBL10537304 | 0.80 | MDH1 (0.65) | MDH1MDH2HIF1AEPAS1MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140044684-A1 | Methods And Compositions For Regulating Gene Expression | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2014-02-13 | — | — | US | claimed |