Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | BID | P55957 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.35 |
| ▸ | BCL2L10 | Q9HD36 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15480780 | 0.81 | ALDH1A1 (0.44) | KDM4ELMNAHPGDALDH1A1NPC1 | |
| SCHEMBL15534635 | 0.79 | ALDH1A1 (0.57) | KDM4ELMNAHPGDALDH1A1NPC1 | |
| SCHEMBL15480774 | 0.79 | ALDH1A1 (0.57) | KDM4ELMNAHPGDALDH1A1NPC1 | |
| SCHEMBL15480784 | 0.79 | ALDH1A1 (0.57) | KDM4ELMNAHPGDALDH1A1NPC1 | |
| SCHEMBL15476462 | 0.79 | ALDH1A1 (0.57) | KDM4ELMNAHPGDALDH1A1NPC1 | |
| SCHEMBL8515079 | 0.79 | ALDH1A1 (0.57) | KDM4ELMNAHPGDALDH1A1NPC1 | |
| SCHEMBL15535350 | 0.79 | ALDH1A1 (0.57) | KDM4ELMNAHPGDALDH1A1NPC1 | |
| SCHEMBL8514055 | 0.73 | TAS1R3 (0.44) | KDM4ELMNAHPGDALDH1A1NPC1 | |
| SCHEMBL15480782 | 0.73 | TAS1R3 (0.44) | KDM4ELMNAHPGDALDH1A1NPC1 | |
| SCHEMBL8514066 | 0.73 | TAS1R3 (0.44) | KDM4ELMNAHPGDALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140051678-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX III OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF FOR TREATING DISEASES | STEMERGIE BIOTECHNOLOGY SA (CH) | 2014-02-20 | — | — | US | disclosed |
| US-20140051678-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX III OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF FOR TREATING DISEASES | STEMERGIE BIOTECHNOLOGY SA (CH) | 2014-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051678-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX III OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF FOR TREATING DISEASES | SQOR, MT-ND3, MT-CO3 | CCR6 4844/4885KDM4E 3660/4885LMNA 3124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.