Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15535350 | 1.00 | ALDH1A1 (0.57) | ALDH1A1LMNANPC1KDM4ERAB9A | |
| SCHEMBL15476462 | 1.00 | ALDH1A1 (0.57) | ALDH1A1LMNANPC1KDM4ERAB9A | |
| SCHEMBL15480774 | 1.00 | ALDH1A1 (0.57) | ALDH1A1LMNANPC1KDM4ERAB9A | |
| SCHEMBL15534635 | 1.00 | ALDH1A1 (0.57) | ALDH1A1LMNANPC1KDM4ERAB9A | |
| SCHEMBL8515079 | 1.00 | ALDH1A1 (0.57) | ALDH1A1LMNANPC1KDM4ERAB9A | |
| SCHEMBL15480781 | 0.89 | TAS1R3 (0.50) | ALDH1A1LMNANPC1KDM4ERAB9A | |
| SCHEMBL15534701 | 0.87 | HTR2B (0.50) | ALDH1A1LMNANPC1KDM4ERAB9A | |
| SCHEMBL15536636 | 0.87 | HTR2B (0.50) | ALDH1A1LMNANPC1KDM4ERAB9A | |
| SCHEMBL15480780 | 0.87 | ALDH1A1 (0.44) | ALDH1A1LMNANPC1KDM4ERAB9A | |
| SCHEMBL15536452 | 0.84 | LIPG (0.50) | ALDH1A1LMNANPC1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140051678-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX III OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF FOR TREATING DISEASES | STEMERGIE BIOTECHNOLOGY SA (CH) | 2014-02-20 | — | — | US | disclosed |
| US-20140051678-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX III OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF FOR TREATING DISEASES | STEMERGIE BIOTECHNOLOGY SA (CH) | 2014-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051678-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX III OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF FOR TREATING DISEASES | SQOR, MT-ND3, MT-CO3 | ALDH1A1 420/4885LMNA 3124/4885NPC1 558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.