SCHEMBL15499062

SCHEMBL15499062

Cc1ccc(N2CCN(CC3CCC(C)CC3)CC2)cc1

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
NPSR1 Q6W5P4 1/20 0.47
DRD2 P14416 2/20 0.45
DRD3 P35462 2/20 0.45
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HTR7 P34969 1/20 0.43
ADRB1 P08588 1/20 0.42
ACHE P22303 1/20 0.42
CYP17A1 P05093 1/20 0.41
CYP21A2 P08686 1/20 0.41
CYP11B1 P15538 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12082219 0.94 MAPT (0.51) MAPTNPSR1DRD2DRD3MEN1
SCHEMBL15499061 0.91 MAPT (0.44) MAPTNPSR1DRD2DRD3MEN1
SCHEMBL22542091 0.87 MAPT (0.51) MAPTNPSR1DRD2DRD3MEN1
SCHEMBL18872636 0.86 MAPT (0.46) MAPTNPSR1DRD2DRD3HTR7
SCHEMBL24803641 0.84 MAPT (0.43) MAPTNPSR1DRD2DRD3HTR7
SCHEMBL24834707 0.81 MAPT (0.47) MAPTNPSR1DRD2DRD3KMT2A
SCHEMBL12073571 0.79 CHRM5 (0.48) MAPTMEN1KMT2AADRB1
SCHEMBL20372819 0.79 MAPT (0.51) MAPTNPSR1HTR7ADRB1
SCHEMBL17665100 0.79 MAPT (0.48) MAPTNPSR1DRD2DRD3MEN1
SCHEMBL17432874 0.78 CCR2 (0.47) DRD2DRD3ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160366909-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE AS ANIMAL FEED AND METHODS OF PRODUCING THEREOF MIDORI USA, INC. (US) 2016-12-22 US disclosed
US-20160032038-A1 POLYMERIC IONIC SALT CATALYSTS AND METHODS OF PRODUCING THEREOF MIDORI USA, INC. (US) 2016-02-04 US disclosed
US-9238845-B2 Methods of producing sugars from biomass feedstocks MIDORI USA, INC. (US) 2016-01-19 US disclosed
US-20150202607-A1 POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING CELLULOSIC MATERIALS USING SUCH CATALYSTS Midori Renewables, Inc. (US) 2015-07-23 US disclosed
US-20140060522-A1 METHODS OF PRODUCING SUGARS FROM BIOMASS FEEDSTOCKS HERCULES CAPITAL, INC. 2014-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160366909-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE AS ANIMAL FEED AND METHODS OF PRODUCING THEREOF FUT5, FUT6, OSTC MAPT 3577/4885NPSR1 3212/4885DRD2 4449/4885
US-20150202607-A1 POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING CELLULOSIC MATERIALS USING SUCH CATALYSTS MGAM, CEL, SI MAPT 4450/4885NPSR1 3574/4885DRD2 4537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.