Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Phosphonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL15510586 | 1.00 | TDP1 (0.63) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Phosphonic Acid SCHEMBL7871109 | 0.97 | TDP1 (0.67) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Phosphonic Acid SCHEMBL15511192 | 0.95 | TDP1 (0.63) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Phosphonic Acid SCHEMBL15511191 | 0.95 | TDP1 (0.63) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Phosphonic Acid SCHEMBL28820202 | 0.92 | CYP3A4 (0.60) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Acetic Acid SCHEMBL15511068 | 0.88 | CYP3A4 (0.55) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Phosphonic Acid SCHEMBL15511198 | 0.88 | TDP1 (0.55) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Sulfuric Acid SCHEMBL15511079 | 0.88 | TDP1 (0.55) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL4944650 | 0.87 | CYP3A4 (0.60) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Phosphonic Acid SCHEMBL15572106 | 0.85 | CYP3A4 (0.57) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736245-B | Polymeric and solid-supported catalysts, and methods of digesting cellulosic materials using such catalysts | 米德瑞（美国）有限公司 | 2017-04-12 | — | — | CN | claimed |
| US-20150202607-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING CELLULOSIC MATERIALS USING SUCH CATALYSTS | Midori Renewables, Inc. (US) | 2015-07-23 | — | — | US | claimed |
| CN-104736245-A | Polymeric and solid-supported catalysts, and methods of digesting cellulosic materials using such catalysts | MIDORI RENEWABLES INC | 2015-06-24 | — | — | CN | claimed |
| US-20230255240-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE AS ANIMAL FEED AND METHODS OF PRODUCING THEREOF | MIDORI USA, INC. | 2023-08-17 | — | — | US | disclosed |
| EP-4209130-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF | DSM Nutritional Products, LLC (US) | 2023-07-12 | — | — | EP | disclosed |
| EP-4205553-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF | DSM Nutritional Products, LLC (US) | 2023-07-05 | — | — | EP | disclosed |
| US-11653676-B2 | Oligosaccharide compositions for use as animal feed and methods of producing thereof | DSM NUTRITIONAL PRODUCTS, LLC (US) | 2023-05-23 | — | — | US | disclosed |
| US-11584805-B2 | Oligosaccharide compositions and methods for producing thereof | DSM NUTRITIONAL PRODUCTS, LLC (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220409644-A1 | ANIMAL THERAPEUTIC AND FEED COMPOSITIONS AND METHODS OF USE | DSM NUTRITIONAL PRODUCTS, LLC | 2022-12-29 | — | — | US | disclosed |
| US-20220400728-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE AS FOOD INGREDIENTS AND METHODS OF PRODUCING THEREOF | CADENA BIO INC (US) | 2022-12-22 | — | — | US | disclosed |
| US-20210352945-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE IN NUTRITIONAL COMPOSITIONS, AND METHODS OF PRODUCING THEREOF | HERCULES CAPITAL, INC. | 2021-11-18 | — | — | US | disclosed |
| WO-2016122885-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE IN NUTRITIONAL COMPOSITIONS, AND METHODS OF PRODUCING THEREOF | MIDORI USA, INC. (US) | 2016-08-04 | — | — | WO | disclosed |
| WO-2016122887-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF | MIDORI USA, INC. (US) | 2016-08-04 | — | — | WO | disclosed |
| WO-2016122884-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE AS FOOD INGREDIENTS AND METHODS OF PRODUCING THEREOF | MIDORI USA, INC. (US) | 2016-08-04 | — | — | WO | disclosed |
| US-9238845-B2 | Methods of producing sugars from biomass feedstocks | MIDORI USA, INC. (US) | 2016-01-19 | — | — | US | disclosed |
| US-20160007642-A1 | OLIGOSACCHARIDE COMPOSITIONS AND METHODS FOR PRODUCING THEREOF | MIDORI USA, INC. (US) | 2016-01-14 | — | — | US | disclosed |
| WO-2016007778-A1 | OLIGOSACCHARIDE COMPOSITIONS AND METHODS FOR PRODUCING THEREOF | MIDORI USA, INC. (US) | 2016-01-14 | — | — | WO | disclosed |
| US-20150202607-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING CELLULOSIC MATERIALS USING SUCH CATALYSTS | Midori Renewables, Inc. (US) | 2015-07-23 | — | — | US | disclosed |
| CN-104736245-A | Polymeric and solid-supported catalysts, and methods of digesting cellulosic materials using such catalysts | MIDORI RENEWABLES INC | 2015-06-24 | — | — | CN | disclosed |
| US-20140060522-A1 | METHODS OF PRODUCING SUGARS FROM BIOMASS FEEDSTOCKS | HERCULES CAPITAL, INC. | 2014-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230255240-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE AS ANIMAL FEED AND METHODS OF PRODUCING THEREOF | FUT5, FUT6, OSTC | TDP1 4759/4885CYP3A4 4177/4885ESR1 4879/4885 |
| US-11584805-B2 | Oligosaccharide compositions and methods for producing thereof | OSTC, FUT5, FUT6 | TDP1 4531/4885CYP3A4 2269/4885ESR1 4812/4885 |
| US-11653676-B2 | Oligosaccharide compositions for use as animal feed and methods of producing thereof | FUT5, FUT6, OSTC | TDP1 4759/4885CYP3A4 4177/4885ESR1 4879/4885 |
| US-20220409644-A1 | ANIMAL THERAPEUTIC AND FEED COMPOSITIONS AND METHODS OF USE | FUT6, FUT5, PIGS | TDP1 4614/4885CYP3A4 4853/4885ESR1 4845/4885 |
| US-20210352945-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE IN NUTRITIONAL COMPOSITIONS, AND METHODS OF PRODUCING THEREOF | OSTC, FUT5, FUT6 | TDP1 4665/4885CYP3A4 3782/4885ESR1 4881/4885 |
| US-20150202607-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING CELLULOSIC MATERIALS USING SUCH CATALYSTS | MGAM, CEL, SI | TDP1 920/4885CYP3A4 1469/4885ESR1 4531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.