Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15512227 | 0.78 | KDM4E (0.36) | GAAALDH1A1KDM4E | |
| SCHEMBL27922097 | 0.77 | MEN1 (0.33) | ALDH1A1KDM4E | |
| SCHEMBL18230673 | 0.74 | KEAP1 (0.43) | ALDH1A1KDM4E | |
| SCHEMBL21049522 | 0.72 | KEAP1 (0.41) | ALDH1A1KDM4E | |
| SCHEMBL503668 | 0.67 | KDM4E (0.57) | POLBGAAALDH1A1KDM4E | |
| SCHEMBL9957368 | 0.67 | KDM4E (0.34) | GAAALDH1A1KDM4E | |
| SCHEMBL15512617 | 0.66 | TSHR (0.30) | ALDH1A1 | |
| SCHEMBL22840863 | 0.66 | KDM4E (0.55) | POLBGAAALDH1A1KDM4E | |
| SCHEMBL525957 | 0.66 | KDM4E (0.55) | POLBGAAALDH1A1KDM4E | |
| SCHEMBL6693141 | 0.65 | POLB (0.58) | POLBGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895517-B1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| US-20150259465-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2015-09-17 | — | — | US | disclosed |
| EP-2895517-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | Sika Technology AG (CH) | 2015-07-22 | — | — | EP | disclosed |
| WO-2014040922-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2014-03-20 | — | — | WO | disclosed |
| EP-2706073-A1 | Two-component polyurethane composition | Sika Technology AG (CH) | 2014-03-12 | — | — | EP | disclosed |