Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936058 | 0.88 | KDM4E (0.38) | KDM4EALDH1A1 | |
| SCHEMBL9935441 | 0.77 | TDP1 (0.33) | ALDH1A1PAOX | |
| SCHEMBL30998792 | 0.75 | TDP1 (0.46) | KDM4EALDH1A1PAOX | |
| SCHEMBL15512227 | 0.74 | KDM4E (0.36) | KDM4EALDH1A1GAA | |
| SCHEMBL18230673 | 0.71 | KEAP1 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL27922097 | 0.70 | MEN1 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL31687256 | 0.70 | TDP1 (0.43) | KDM4EALDH1A1PAOX | |
| SCHEMBL21049522 | 0.69 | KEAP1 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL9935811 | 0.65 | PAOX (0.31) | ALDH1A1PAOX | |
| SCHEMBL125043 | 0.65 | SMN1; SMN2 (0.48) | KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861642-B1 | SILANE-FUNCTIONAL POLYMER | SIKA TECH AG (CH) | 2018-10-17 | — | — | EP | disclosed |
| CN-103313995-B | Secondary aminosilanes | SIKA技术股份公司 | 2016-08-10 | — | — | CN | disclosed |
| EP-2861642-A1 | POLYMER CONTAINING SILANE GROUPS | Sika Technology AG (CH) | 2015-04-22 | — | — | EP | disclosed |
| US-8877955-B2 | Secondary aminosilanes | SIKA TECHNOLOGY AG (CH) | 2014-11-04 | — | — | US | disclosed |
| WO-2013186349-A1 | POLYMER CONTAINING SILANE GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-12-19 | — | — | WO | disclosed |
| US-20130281562-A1 | SECONDARY AMINOSILANES | SIKA TECHNOLOGY AG (CH) | 2013-10-24 | — | — | US | disclosed |
| CN-103313995-A | Secondary aminosilanes | SIKA TECHNOLOGY AG | 2013-09-18 | — | — | CN | disclosed |
| EP-2468759-A1 | Secondary Aminosilanes | Sika Technology AG (CH) | 2012-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281562-A1 | SECONDARY AMINOSILANES | AS3MT, SRM, MSN | KDM4E 990/4885ALDH1A1 1639/4885PAOX 3703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.