Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21049522 | 0.94 | KEAP1 (0.41) | KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL15512227 | 0.89 | KDM4E (0.36) | KEAP1SMN1; SMN2KDM4EALDH1A1ALOX15 | |
| SCHEMBL27922097 | 0.81 | MEN1 (0.33) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9936058 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1 | |
| SCHEMBL15512437 | 0.74 | POLB (0.40) | KDM4EALDH1A1 | |
| SCHEMBL9957368 | 0.71 | KDM4E (0.34) | KDM4EALDH1A1 | |
| SCHEMBL28020854 | 0.70 | SMN1; SMN2 (0.40) | KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL342075 | 0.68 | SMN1; SMN2 (0.40) | KEAP1SMN1; SMN2KDM4EALDH1A1ALOX15 | |
| SCHEMBL28301264 | 0.66 | MEN1 (0.35) | KEAP1SMN1; SMN2KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL3978411 | 0.65 | SMN1; SMN2 (0.43) | KEAP1SMN1; SMN2KDM4EALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294803-A1 | CATALYST CONTAINING GUANIDINE GROUPS | Sika Technology AG (CH) | 2018-03-21 | — | — | EP | disclosed |
| WO-2016180840-A1 | CATALYST CONTAINING GUANIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2016-11-17 | — | — | WO | disclosed |