Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230673 | 0.94 | KEAP1 (0.43) | KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL15512227 | 0.93 | KDM4E (0.36) | KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27922097 | 0.79 | MEN1 (0.33) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9936058 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1 | |
| SCHEMBL28020854 | 0.73 | SMN1; SMN2 (0.40) | KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9957368 | 0.69 | KDM4E (0.34) | KDM4EALDH1A1 | |
| SCHEMBL23356551 | 0.69 | DHPS (0.38) | ALDH1A1 | |
| SCHEMBL342075 | 0.66 | SMN1; SMN2 (0.40) | KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5988693 | 0.65 | KEAP1 (0.83) | KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5903339 | 0.65 | KEAP1 (0.83) | KEAP1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110684501-B | Polyurethane hard foam powder filled single-component polyurethane sealant and preparation method thereof | 郑州大学 | 2022-03-22 | — | — | CN | claimed |
| CN-110684501-A | Polyurethane hard foam powder filled single-component polyurethane sealant and preparation method thereof | 郑州骏惠材料技术有限公司 | 2020-01-14 | — | — | CN | claimed |
| CN-116490493-A | Moisture-curable polyurethane compositions | SIKA技术股份公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-109923139-B | Two-component polyurethane sealants for low temperature applications | SIKA技术股份公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-109563232-B | Two-component polyurethane adhesive with mechanical properties substantially unaffected by temperature and high strength | SIKA技术股份公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-110684501-B | Polyurethane hard foam powder filled single-component polyurethane sealant and preparation method thereof | 郑州大学 | 2022-03-22 | — | — | CN | disclosed |
| EP-3833701-A1 | POLYURETHANE COMPOSITION HAVING A LOW CONTENT OF MONOMERIC DIISOCYANTES | Sika Technology AG (CH) | 2021-06-16 | — | — | EP | disclosed |
| CN-112533972-A | Polyurethane compositions with low content of monomeric diisocyanates | SIKA技术股份公司 | 2021-03-19 | — | — | CN | disclosed |
| WO-2020030607-A1 | POLYURETHANE COMPOSITION HAVING A LOW CONTENT OF MONOMERIC DIISOCYANTES | SIKA TECHNOLOGY AG (CH) | 2020-02-13 | — | — | WO | disclosed |
| CN-110684501-A | Polyurethane hard foam powder filled single-component polyurethane sealant and preparation method thereof | 郑州骏惠材料技术有限公司 | 2020-01-14 | — | — | CN | disclosed |
| EP-3494155-A1 | TWO-COMPONENT POLYURETHANE ADHESIVE HAVING SUBSTANTIALLY TEMPERATURE-INDEPENDENT MECHANICAL PROPERTIES AND HIGH STRENGTH | Sika Technology AG (CH) | 2019-06-12 | — | — | EP | disclosed |
| CN-104640894-A | Two-component polyurethane composition | SIKA TECHNOLOGY AG | 2015-05-20 | — | — | CN | disclosed |