Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL268986 | 0.94 | LMNA (0.36) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13492209 | 0.93 | LMNA (0.35) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1704092 | 0.88 | LMNA (0.35) | LMNAPSEN1PSEN2APH1BNCSTN | |
| Bemotrizinol SCHEMBL7526147 | 0.83 | TDP1 (0.38) | LMNAALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7217044 | 0.82 | LMNA (0.42) | LMNAALDH1A1CA2CYP3A4TSHR | |
| SCHEMBL3223605 | 0.81 | CYP3A4 (0.42) | LMNAALDH1A1CA2CYP3A4TSHR | |
| SCHEMBL3226436 | 0.80 | LMNA (0.35) | LMNAALDH1A1CA2CYP3A4TSHR | |
| SCHEMBL28638598 | 0.79 | LMNA (0.40) | LMNAALDH1A1CA2CYP3A4TSHR | |
| SCHEMBL28482241 | 0.79 | LMNA (0.37) | LMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL6705841 | 0.78 | GPR88 (0.35) | LMNAALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313076-A2 | RINSE-OFF PRODUCTS HAVING A BENEFICIAL EFFECT ON THE SKIN | Henkel AG & Co. KGaA (DE) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010003843-A2 | RINSE-OFF PRODUCTS HAVING A BENEFICIAL EFFECT ON THE SKIN | HENKEL AG & CO. KGAA (DE) | 2010-01-14 | — | — | WO | disclosed |