SCHEMBL1704092

SCHEMBL1704092

CCCCC(CC)COc1ccc(-c2ncnc(-c3cccn3C)n2)c(O)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.35
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33
ALDH1A1 P00352 5/20 0.33
CYP3A4 P08684 2/20 0.33
CA2 P00918 1/20 0.33
MAPK1 P28482 2/20 0.32
TSHR P16473 1/20 0.32
HRH3 Q9Y5N1 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL268986 0.93 LMNA (0.36) LMNAPSEN1PSEN2APH1BNCSTN
SCHEMBL13492209 0.91 LMNA (0.35) LMNAPSEN1PSEN2APH1BNCSTN
SCHEMBL1551245 0.88 LMNA (0.33) LMNAPSEN1PSEN2APH1BNCSTN
SCHEMBL579788 0.88 LMNA (0.40) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL29365165 0.88 LMNA (0.40) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL18979221 0.83 LMNA (0.40) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL21964022 0.83 LMNA (0.34) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL7217044 0.82 LMNA (0.42) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL28535053 0.82 LMNA (0.40) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL28344806 0.82 LMNA (0.39) LMNAALDH1A1CYP3A4CA2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1649900-B1 Light screening composition comprising a derivative of dibenzoylmethane, a bis-resorcinyl triazine and a compound capable of accepting energy of the excited triplet state of dibenzoylmethane; process for photostabilisation OREAL (FR) 2012-04-18 EP claimed
EP-1927345-B1 Cosmetic composition containing the combination of a silicon-containing s-triazine substituted with two aminobenzoate or aminobenzamide groups and a silicon-free lipophilic triazine UV-screening agent OREAL (FR) 2012-01-18 EP claimed
EP-1927345-A1 Cosmetic composition containing the combination of a silicon-containing s-triazine substituted with two aminobenzoate or aminobenzamide groups and a non-silicon-containing lipophilic triazine uv-screening agent L'Oréal (FR) 2008-06-04 EP claimed
EP-1649900-A2 Light screening composition comprising a derivative of dibenzoylmethane, a bis-resorcinyl triazine and a compound capable of accepting energy of the excited triplet state of dibenzoylmethane; process for photostabilisation L'OREAL (FR) 2006-04-26 EP claimed
EP-1618868-A1 Process for photostabilising a dibenzoylmethane derivative with an arylalkyl benzoate derivative and a bis-resorcinyl triazine compound and sunscreening cosmetic compositions L'OREAL (FR) 2006-01-25 EP claimed
EP-1040820-B1 Cosmetic sunscreen compositions based on synergic filter mixtures and their uses OREAL (FR) 2004-06-23 EP claimed
EP-1355622-A1 FILTERING COMPOSITIONS COMPRISING A 1,3,5-TRIAZINE DERIVATIVE AND A TRICARBOXYLIC ACID TRIESTER AND USES THEREOF L'OREAL (FR) 2003-10-29 EP claimed
WO-2002056851-A1 FILTERING COMPOSITIONS COMPRISING A 1,3,5-TRIAZINE DERIVATIVE AND A TRICARBOXYLIC ACID TRIESTER AND USES THEREOF L'OREAL (FR) 2002-07-25 WO claimed
EP-1043014-A1 Cosmetic sunscreen compositions based on a synergic filter mixture and their uses L'OREAL (FR) 2000-10-11 EP claimed
EP-1043013-A1 Photoprotective compositions containing a benzotriazole derivative, a bis-resorcinyl triazine derivative and a compound having benzoazolyl- or benzodiazolyl groups L'OREAL (FR) 2000-10-11 EP claimed
EP-1040820-A1 Cosmetic sunscreen compositions based on synergic filter mixtures and their uses L'OREAL (FR) 2000-10-04 EP claimed
EP-1027881-A1 Photoprotective compositions containing a bisresorcinyl triazine derivative and a compound with benzoazolyl or benzodiazolyl groups L'OREAL (FR) 2000-08-16 EP claimed
WO-2023110815-A1 EMULSION WITH ALPHA-HYDROXY ACID, UV FILTER AND POLYMER L'OREAL (FR) 2023-06-22 WO disclosed
US-11191710-B2 Photoprotective cosmetic composition and process for obtaining the same L'OREAL (FR) 2021-12-07 US disclosed
US-20190000738-A1 PHOTOPROTECTIVE COSMETIC COMPOSITION AND PROCESS FOR OBTAINING THE SAME L'OREAL (FR) 2019-01-03 US disclosed
US-20180369111-A1 COMPOSITION COMPRISING BAICALIN AT A HIGH CONCENTRATION L'OREAL (FR) 2018-12-27 US disclosed
EP-1043014-A1 Cosmetic sunscreen compositions based on a synergic filter mixture and their uses L'OREAL (FR) 2000-10-11 EP disclosed
EP-1040820-A1 Cosmetic sunscreen compositions based on synergic filter mixtures and their uses L'OREAL (FR) 2000-10-04 EP disclosed
WO-2000047176-A1 COSMETIC COMPOSITIONS FOR PHOTOPROTECTION OF THE SKIN AND/OR HAIR CONTAINING A BENZOTRIAZOLE DERIVATIVE AND A TRIAZINE BIS-RESORCINYL L'OREAL (FR) 2000-08-17 WO disclosed
EP-1027881-A1 Photoprotective compositions containing a bisresorcinyl triazine derivative and a compound with benzoazolyl or benzodiazolyl groups L'OREAL (FR) 2000-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11191710-B2 Photoprotective cosmetic composition and process for obtaining the same MGLL, DAGLB, LIPC LMNA 810/4885PSEN1 2760/4885PSEN2 2009/4885
US-20190000738-A1 PHOTOPROTECTIVE COSMETIC COMPOSITION AND PROCESS FOR OBTAINING THE SAME MGLL, DAGLB, LIPC LMNA 810/4885PSEN1 2760/4885PSEN2 2009/4885
US-20180369111-A1 COMPOSITION COMPRISING BAICALIN AT A HIGH CONCENTRATION PLIN5, IL5, PLIN3 LMNA 3026/4885PSEN1 2283/4885PSEN2 1946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.