Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL948973 | 0.82 | GPR119 (0.50) | F10OPRD1KDM4E | |
| SCHEMBL16419181 | 0.81 | ALDH1A1 (0.48) | F10PIM1FDPSBRD4KDM4E | |
| SCHEMBL28192282 | 0.77 | KDM4E (0.50) | F10OPRD1PIM1BRD4KDM4E | |
| SCHEMBL23204979 | 0.74 | BRD4 (0.54) | F10PIM1BRD4KDM4EALDH1A1 | |
| SCHEMBL1181466 | 0.74 | BRD4 (0.55) | F10PIM1FDPSBRD4KDM4E | |
| Hydrochloric Acid SCHEMBL28784813 | 0.73 | BRD4 (0.54) | F10PIM1BRD4KDM4EALDH1A1 | |
| SCHEMBL15515146 | 0.72 | NOTUM (0.37) | BRD4HTR2B | |
| SCHEMBL8544090 | 0.72 | FAAH (0.51) | F10OPRD1HTR2B | |
| SCHEMBL1582097 | 0.72 | MTNR1A (0.46) | — | |
| SCHEMBL11983333 | 0.71 | SMN1; SMN2 (0.47) | KDM4EALPLALPIALPGPLAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10188642-B2 | Pharmacologically active compounds | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2019-01-29 | — | — | US | disclosed |
| US-20180117032-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2018-05-03 | — | — | US | disclosed |
| US-9895364-B2 | Pharmacologically active compounds | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2018-02-20 | — | — | US | disclosed |
| EP-2892890-B1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS | CANCER RES TECH LTD (GB) | 2017-11-22 | — | — | EP | disclosed |
| US-20160296514-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS | INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE) (GB) | 2016-10-13 | — | — | US | disclosed |
| US-9334286-B2 | Pharmacologically active compounds | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2016-05-10 | — | — | US | disclosed |
| US-20150218181-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2015-08-06 | — | — | US | disclosed |
| EP-2892890-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS | Cancer Research Technology Ltd (GB) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014037751-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2014-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218181-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS | BUB1B, BUB1, PLK1 | F10 4147/4885OPRD1 4091/4885PIM1 1458/4885 |
| US-20180117032-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS | BUB1B, BUB1, PLK1 | F10 4147/4885OPRD1 4091/4885PIM1 1458/4885 |
| US-10188642-B2 | Pharmacologically active compounds | BUB1B, BUB1, PLK1 | F10 4147/4885OPRD1 4091/4885PIM1 1458/4885 |
| US-20160296514-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS | BUB1B, BUB1, PLK1 | F10 4147/4885OPRD1 4091/4885PIM1 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.