Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890915 | 0.84 | GAA (0.51) | POLBCYP1A2GAATSHRHNF4A | |
| SCHEMBL27488099 | 0.82 | ALDH1A1 (0.54) | TSHRHNF4ACA12CA1CA2 | |
| SCHEMBL26502 | 0.77 | HNF4A (0.53) | GAATSHRHNF4AALDH1A1ALOX15 | |
| SCHEMBL8761962 | 0.77 | POLB (0.68) | POLBCYP1A2GAACA12CA1 | |
| SCHEMBL4630736 | 0.76 | ALDH1A1 (0.55) | TSHRHNF4ACA12CA1CA2 | |
| SCHEMBL4777002 | 0.76 | TSHR (0.59) | TSHRHNF4ACA1CA2CA9 | |
| SCHEMBL5455144 | 0.75 | ALDH1A1 (0.57) | CYP1A2TSHRHNF4AALDH1A1ALOX15 | |
| SCHEMBL9717027 | 0.75 | ALDH1A1 (0.53) | TSHRHNF4ACA12CA1CA2 | |
| SCHEMBL18836973 | 0.75 | LMNA (0.50) | TSHRHNF4ACA12CA1CA2 | |
| SCHEMBL3361334 | 0.75 | MMP2 (0.52) | GAATSHRHNF4AALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8544658-B2 | Functionalized thin film polyamide membranes | POLYMERS CRC LIMITED (AU) | 2013-10-01 | — | — | US | disclosed |
| EP-2313184-B1 | FUNCTIONALIZED THIN FILM POLYAMIDE MEMBRANES | POLYMERS CRC LTD (AU) | 2012-10-10 | — | — | EP | disclosed |
| US-20110189469-A1 | FUNCTIONALIZED THIN FILM POLYAMIDE MEMBRANES | POLYMERS CRC LIMITED (AU) | 2011-08-04 | — | — | US | disclosed |
| EP-2313184-A1 | FUNCTIONALIZED THIN FILM POLYAMIDE MEMBRANES | Polymers CRC Limited (AU) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010015599-A1 | FUNCTIONALIZED THIN FILM POLYAMIDE MEMBRANES | POLYMERS CRC LIMITED (AU) | 2010-02-11 | — | — | WO | disclosed |