SCHEMBL1551776

SCHEMBL1551776

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCOS(C)(=O)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
ALOX15 P16050 3/20 0.54
KDM4E B2RXH2 2/20 0.54
LMNA P02545 2/20 0.54
TSHR P16473 2/20 0.54
USP2 O75604 1/20 0.54
MMP9 P14780 1/20 0.54
F7 P08709 3/20 0.46
F3 P13726 3/20 0.46
CYP19A1 P11511 3/20 0.46
MAPT P10636 2/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
OXER1 Q8TDS5 2/20 0.46
PTGS1 P23219 2/20 0.46
PPARG P37231 2/20 0.46
KMT2A Q03164 2/20 0.46
PPARD Q03181 2/20 0.46
PPARA Q07869 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1551778 1.00 ALDH1A1 (0.54) ALDH1A1ALOX15KDM4ELMNATSHR
SCHEMBL247028 0.98 ALDH1A1 (0.52) ALDH1A1ALOX15KDM4ELMNATSHR
SCHEMBL3490050 0.98 ALDH1A1 (0.52) ALDH1A1ALOX15KDM4ELMNATSHR
SCHEMBL16503992 0.95 ALDH1A1 (0.50) ALDH1A1ALOX15KDM4ELMNATSHR
SCHEMBL23294916 0.93 ALDH1A1 (0.58) ALDH1A1ALOX15KDM4ELMNATSHR
SCHEMBL8985903 0.93 ALDH1A1 (0.58) ALDH1A1ALOX15KDM4ELMNATSHR
SCHEMBL21626134 0.93 ALDH1A1 (0.58) ALDH1A1ALOX15KDM4ELMNATSHR
SCHEMBL1046506 0.89 FAAH (0.54) ALDH1A1ALOX15KDM4ELMNATSHR
SCHEMBL4450423 0.89 FAAH (0.54) ALDH1A1ALOX15KDM4ELMNATSHR
SCHEMBL1046505 0.89 FAAH (0.54) ALDH1A1ALOX15KDM4ELMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12465580-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF AS (NO) 2025-11-11 US disclosed
EP-3288550-B1 STRUCTURALLY ENHANCED FATTY ACIDS CONTAINING SULPHUR FOR THEIR USE IN TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2024-06-05 EP disclosed
US-20240156760-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2024-05-16 US disclosed
US-11911354-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF (NO) 2024-02-27 US disclosed
US-11911354-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF (NO) 2024-02-27 US disclosed
US-11911354-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF (NO) 2024-02-27 US disclosed
CN-115025079-A Use of structurally enhanced sulfur-containing fatty acids for the prevention and/or treatment of non-alcoholic steatohepatitis 普罗诺瓦生物医药挪威公司 2022-09-09 CN disclosed
US-20220280459-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2022-09-08 US disclosed
US-20220280459-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2022-09-08 US disclosed
US-11234948-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF AS (NO) 2022-02-01 US disclosed
US-20140316002-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2014-10-23 US disclosed
US-8759558-B2 Sulphur containing lipids for use as food supplement or as medicament PRONOVA BIOPHARMA NORGE AS (NO) 2014-06-24 US disclosed
US-8759558-B2 Sulphur containing lipids for use as food supplement or as medicament PRONOVA BIOPHARMA NORGE AS (NO) 2014-06-24 US disclosed
US-8759558-B2 Sulphur containing lipids for use as food supplement or as medicament PRONOVA BIOPHARMA NORGE AS (NO) 2014-06-24 US disclosed
US-20110190395-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2011-08-04 US disclosed
US-20110190395-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2011-08-04 US disclosed
US-20110190395-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2011-08-04 US disclosed
EP-2313090-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT Pronova BioPharma Norge AS (NO) 2011-04-27 EP disclosed
WO-2010008299-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2010-01-21 WO disclosed
WO-2010008299-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2010-01-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465580-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis SLC10A1, LIPC, FABP1 ALDH1A1 443/4885ALOX15 166/4885KDM4E 2114/4885
US-20140316002-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT SGMS2, SGMS1, ACSS2 ALDH1A1 514/4885ALOX15 226/4885KDM4E 2212/4885
US-20240156760-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS SLC10A1, LIPC, FABP1 ALDH1A1 443/4885ALOX15 166/4885KDM4E 2114/4885
US-11234948-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis SLC10A1, LIPC, FABP1 ALDH1A1 443/4885ALOX15 166/4885KDM4E 2114/4885
US-20110190395-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT SGMS2, SGMS1, ACSS2 ALDH1A1 514/4885ALOX15 226/4885KDM4E 2212/4885
US-20220280459-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS SLC10A1, LIPC, FABP1 ALDH1A1 443/4885ALOX15 166/4885KDM4E 2114/4885
US-11911354-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis SLC10A1, LIPC, FABP1 ALDH1A1 443/4885ALOX15 166/4885KDM4E 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.