Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15504569 | 0.88 | KIT (0.66) | KIT | |
| SCHEMBL15519250 | 0.84 | KIT (1.00) | KIT | |
| SCHEMBL15504570 | 0.70 | KIT (0.60) | KIT | |
| SCHEMBL23536398 | 0.68 | SHMT2 (0.35) | KIT | |
| SCHEMBL21332385 | 0.67 | LIMK1 (0.43) | KIT | |
| SCHEMBL21339637 | 0.67 | KIT (0.42) | KIT | |
| SCHEMBL15514920 | 0.66 | KIT (1.00) | KIT | |
| SCHEMBL15504537 | 0.64 | KIT (0.78) | KIT | |
| SCHEMBL25236318 | 0.64 | LIMK1 (0.39) | — | |
| SCHEMBL18865732 | 0.63 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892534-A2 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | Plexxikon, Inc. (US) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014039714-A2 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2014-03-13 | — | — | WO | disclosed |