Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | RAD52 | P43351 | 2/20 | 0.47 |
| ▸ | GAPDH | P04406 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL29587501 | 1.00 | SNCA (0.59) | SNCAALOX15ALOX12MEN1RECQL | |
| SCHEMBL17138368 | 0.93 | SNCA (0.67) | SNCAALOX15ALOX12MEN1RECQL | |
| SCHEMBL1278365 | 0.93 | SNCA (0.67) | SNCAALOX15ALOX12MEN1RECQL | |
| SCHEMBL2728671 | 0.76 | SNCA (0.67) | SNCAALOX15ALOX12MEN1RECQL | |
| SCHEMBL12682382 | 0.75 | SNCA (1.00) | SNCAALOX15ALOX12MEN1RECQL | |
| SCHEMBL16969066 | 0.75 | SNCA (0.46) | SNCAALOX15ALOX12RECQLTDP1 | |
| SCHEMBL12776823 | 0.73 | SNCA (0.74) | SNCAALOX15ALOX12MEN1RECQL | |
| SCHEMBL9490282 | 0.73 | SNCA (0.74) | SNCAALOX15ALOX12MEN1RECQL | |
| SCHEMBL10510219 | 0.71 | ALDH1A1 (0.46) | SNCAALOX15ALOX12MEN1RECQL | |
| SCHEMBL8709893 | 0.70 | THRB (0.56) | ALOX15MEN1RECQLKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895535-B1 | COMPOSITE MATERIALS AND THEIR USES AS WELL AS METHODS FOR THE PREPARATION THEREOF | ETH Zürich (CH) | 2017-07-19 | — | — | EP | disclosed |
| US-20150218337-A1 | COMPOSITE MATERIALS AND THEIR USES AS WELL AS METHODS FOR THE PREPARATION THEREOF | ETH ZURICH (CH) | 2015-08-06 | — | — | US | disclosed |
| EP-2895535-A2 | COMPOSITE MATERIALS AND THEIR USES AS WELL AS METHODS FOR THE PREPARATION THEREOF | ETH Zürich (CH) | 2015-07-22 | — | — | EP | disclosed |
| WO-2014040704-A2 | COMPOSITE MATERIALS AND THEIR USES AS WELL AS METHODS FOR THE PREPARATION THEREOF | ETH ZURICH (CH) | 2014-03-20 | — | — | WO | disclosed |
| EP-2708571-A1 | Composite materials and their uses as well as methods for the preparation thereof | ETH Zürich (CH) | 2014-03-19 | — | — | EP | disclosed |