Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | PPARD | Q03181 | 5/20 | 0.35 |
| ▸ | PPARA | Q07869 | 5/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365154 | 0.89 | RXRA (0.39) | PPARGPPARDPSEN1PSEN2APH1B | |
| SCHEMBL15519263 | 0.88 | TRPM8 (0.38) | PPARGPPARDPPARAHTT | |
| SCHEMBL15520715 | 0.84 | PPARG (0.37) | PPARGPPARDPPARAPSEN1PSEN2 | |
| SCHEMBL15520544 | 0.83 | MCL1 (0.35) | PPARGPPARDPTGDR2NOD1MCL1 | |
| SCHEMBL15520421 | 0.80 | PPARG (0.37) | PPARGPPARDPPARANOD1 | |
| SCHEMBL14054088 | 0.80 | NOD1 (0.40) | PPARGPPARDPPARAPSEN1PSEN2 | |
| SCHEMBL14053826 | 0.80 | MRGPRX4 (0.35) | PPARGPPARDPPARANOD1 | |
| SCHEMBL15519981 | 0.80 | TRPM8 (0.36) | PPARGPPARDPPARA | |
| SCHEMBL14124725 | 0.78 | NOD1 (0.40) | PPARGPPARDPPARANOD1HTR6 | |
| SCHEMBL15520543 | 0.78 | RXRA (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | claimed |