Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 6/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519840 | 0.89 | CNR1 (0.39) | RXRARXRBTRPM8CNR1CNR2 | |
| SCHEMBL2365154 | 0.86 | RXRA (0.39) | RXRARXRBTRPM8CNR1CNR2 | |
| SCHEMBL14054259 | 0.80 | CA12 (0.41) | CNR1CNR2 | |
| SCHEMBL15520544 | 0.80 | MCL1 (0.35) | CNR1CNR2ACLY | |
| SCHEMBL15519674 | 0.78 | TRPM8 (0.39) | TRPM8 | |
| SCHEMBL15520182 | 0.78 | PPARG (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14054088 | 0.76 | NOD1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2279719 | 0.74 | TRPM8 (0.43) | TRPM8 | |
| SCHEMBL14124725 | 0.74 | NOD1 (0.40) | — | |
| SCHEMBL15519262 | 0.73 | TRPM8 (0.43) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | claimed |