Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519840 | 0.89 | CNR1 (0.39) | NOD1CNR1CNR2ACLYLMNA | |
| SCHEMBL14054259 | 0.83 | CA12 (0.41) | NOD1CNR1CNR2CYP1A2CYP3A4 | |
| SCHEMBL15520182 | 0.83 | PPARG (0.35) | MCL1NOD1USP2GFERPTGDR2 | |
| SCHEMBL15520543 | 0.80 | RXRA (0.39) | CNR1CNR2ACLY | |
| SCHEMBL15519675 | 0.80 | TRPM8 (0.34) | RORCPPARGPPARDACLYMEN1 | |
| SCHEMBL2365154 | 0.75 | RXRA (0.39) | NOD1CNR1CNR2RORCPPARG | |
| SCHEMBL15519729 | 0.74 | MEN1 (0.37) | RORCACLYMEN1LMNAKMT2A | |
| SCHEMBL14054088 | 0.74 | NOD1 (0.40) | NOD1PPARGPPARDPTGS2 | |
| SCHEMBL14124725 | 0.72 | NOD1 (0.40) | NOD1PPARGPPARDPTGS2 | |
| SCHEMBL12096852 | 0.71 | ACLY (0.53) | CNR1PPARGPPARDACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | claimed |