Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | ALPG | P10696 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722361 | 0.84 | CES2 (0.45) | PKMSMN1; SMN2LMNAALDH1A1ALPG | |
| SCHEMBL30211225 | 0.81 | MDM2 (0.41) | SMN1; SMN2LMNAALDH1A1ALPGHPGD | |
| SCHEMBL157185 | 0.81 | MDM2 (0.41) | SMN1; SMN2LMNAALDH1A1ALPGHPGD | |
| SCHEMBL1720514 | 0.73 | LMNA (0.51) | SMN1; SMN2LMNAALDH1A1ALPGTDP1 | |
| SCHEMBL16397433 | 0.72 | S1PR3 (0.43) | ALDH1A1S1PR3 | |
| SCHEMBL30141158 | 0.72 | TDP1 (0.35) | SMN1; SMN2LMNAALDH1A1ALPGTDP1 | |
| SCHEMBL27554624 | 0.71 | APLNR (0.40) | PKMAPLNRSMN1; SMN2CES2CES1 | |
| SCHEMBL16344945 | 0.71 | APLNR (0.39) | PKMAPLNRSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL20723058 | 0.70 | CES2 (0.42) | SMN1; SMN2ALDH1A1CES2CES1NPC1 | |
| SCHEMBL31384011 | 0.70 | PTGS1 (0.47) | PKMAPLNRGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590340-B1 | INTERMEDIATES FOR THE SYNTHESIS OF FUNGICIDAL PYRAZOLES | FMC CORP (US) | 2023-11-15 | — | — | EP | disclosed |
| US-20180310562-A1 | FUNGICIDAL PYRAZOLE MIXTURES | FMC CORP (US) | 2018-11-01 | — | — | US | disclosed |
| US-10015966-B2 | Fungicidal pyrazole mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-07-10 | — | — | US | disclosed |
| EP-2809157-B1 | FUNGICIDAL PYRAZOLE MIXTURES | DU PONT (US) | 2017-09-06 | — | — | EP | disclosed |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2017-06-01 | — | — | US | disclosed |
| US-9596853-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2015-10-29 | — | — | US | disclosed |
| US-9107412-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-08-18 | — | — | US | disclosed |
| EP-2809157-A2 | FUNGICIDAL PYRAZOLE MIXTURES | E. I. Du Pont de Nemours and Company (US) | 2014-12-10 | — | — | EP | disclosed |
| WO-2014130409-A2 | FUNGICIDAL PYRAZOLE MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-28 | — | — | WO | disclosed |
| WO-2013116251-A2 | FUNGICIDAL PYRAZOLE MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-08-08 | — | — | WO | disclosed |
| EP-2611296-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2012031061-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | PKM 1529/4885APLNR 4458/4885SMN1; SMN2 2600/4885 |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | PKM 1529/4885APLNR 4458/4885SMN1; SMN2 2600/4885 |
| US-10015966-B2 | Fungicidal pyrazole mixtures | CYP1B1, CBR3, CBR1 | PKM 2523/4885APLNR 4651/4885SMN1; SMN2 3555/4885 |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | PKM 1529/4885APLNR 4458/4885SMN1; SMN2 2600/4885 |
| US-20180310562-A1 | FUNGICIDAL PYRAZOLE MIXTURES | CYP1B1, CBR3, CBR1 | PKM 2523/4885APLNR 4651/4885SMN1; SMN2 3555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.